Sleep Physiology, Hypersomnolence, Parasomnias

Description

Sleep lecture given by Dr Ian Morrison on 17/9/2018
Matthew Coulson
Quiz by Matthew Coulson, updated more than 1 year ago
Matthew Coulson
Created by Matthew Coulson about 6 years ago
31
2

Resource summary

Question 1

Question
In terms of sleeping, there are both REM and non-REM cycles. What does 'REM' stand for? [blank_start]Rapid eye movement[blank_end]
Answer
  • Rapid eye movement

Question 2

Question
Which sleep type is most associated with dreaming?
Answer
  • Non-REM
  • REM

Question 3

Question
The average adult spends 75% of their sleep in REM cycles and 25% in non-REM cycles
Answer
  • True
  • False

Question 4

Question
Which type of sleep is similar to wakefulness?
Answer
  • Non-REM sleep
  • REM sleep

Question 5

Question
Which type of sleep is most important for protein synthesis, cell division and growth?
Answer
  • REM sleep
  • Non-REM sleep

Question 6

Question
Melatonin is one of the main regulators of the circadian rhythm (along with cortisol level and low body temperature). Where is melatonin produced? The [blank_start]Pineal Gland[blank_end]
Answer
  • Pineal Gland

Question 7

Question
Light entrains the circadian rhythm in humans: Retinal [blank_start]ganglion[blank_end] cells project information to the [blank_start]suprachiasmatic[blank_end] nucleus in the hypothalamus to regulate sleep-wake cycles.
Answer
  • ganglion
  • bipolar
  • horizontal
  • amacrine
  • Suprachiasmatic
  • Preoptic
  • Paraventricular
  • Arcuate nucleus

Question 8

Question
What is considered the most important stage of sleep, allowing the cerebral hemispheres to effectively 'rest'?
Answer
  • Light Non-REM sleep
  • Deep Non-REM sleep
  • REM sleep

Question 9

Question
A mid afternoon nap of 15 minutes is equivalent to 90 minutes overnight
Answer
  • True
  • False

Question 10

Question
Most studies suggest that 6-6.5 hours of sleep per night is acceptable for adults
Answer
  • True
  • False

Question 11

Question
[blank_start]Narcolepsy[blank_end] is a sleep disorder that is characterized by excessive sleepiness, sleep attacks, sleep paralysis, hallucinations and, for some, sudden loss of muscle control
Answer
  • Narcolepsy

Question 12

Question
The episodes of sudden muscle tone loss that is associated with 70% of narcolepsy patients is known as [blank_start]cataplexy[blank_end]
Answer
  • cataplexy

Question 13

Question
Cataplexy is a sudden loss of muscle tone in response to ...
Answer
  • An emotion such as fear, surprise or joy
  • A transient drop in blood pressure caused by activities such as standing up too quickly
  • Hallucinations that tend to occur spontaneously throughout the day
  • A sudden temperature drop

Question 14

Question
Narcolepsy with cataplexy has a known cause: a loss of cells in the brain that secrete a hormone responsible for wakefulness called ...
Answer
  • Hypocretin
  • Hippocretin
  • Melatonin
  • Hypotonin

Question 15

Question
Investigations for Narcolepsy: [blank_start]Overnight Polysomnography[blank_end]: A comprehensive recording of the biophysiological changes that occur during a normal sleep duration [blank_start]Multiple Sleep Latency Test[blank_end]: Four 25 minute naps around 2 hours apart in order to test brain activity and eye movement [blank_start]Lumbar puncture[blank_end]: Measures the levels of Hypocretin being produced by the brain
Answer
  • Overnight Polysomnography
  • Multiple Sleep Latency Test
  • Lumbar puncture

Question 16

Question
What is REM Behaviour Disorder (RBD)?
Answer
  • A disorder whereby people act out their dreams. The normal atonic nature of muscles during REM sleep is not present.
  • A disorder whereby people actively dream during the day. Like narcolepsy, this condition is also related to hypocretin levels in the brain.
  • A condition whereby an individual wakes up upon initiation of REM sleep, meaning they must sleep in smaller sections and can never get a full night's sleep.

Question 17

Question
Which hormone supplement can be given to REM Behaviour Disorder patients in attempt to improve their sleep? [blank_start]Melatonin[blank_end]
Answer
  • Melatonin

Question 18

Question
Which of the following is the most commonly prescribed medication to treat Narcolepsy?
Answer
  • Modafinil
  • Sodium Oxybate
  • Fluoxetine
  • Amitriptyline
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