Haemalytic Anaemia

Description

Haematology and Anatomy (Red Blood Cells) Quiz on Haemalytic Anaemia, created by gina_evans0312 on 08/01/2014.
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Quiz by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 almost 11 years ago
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Resource summary

Question 1

Question
In normal RBC destruction, globin is recycled and Fe is broken down
Answer
  • True
  • False

Question 2

Question
In Intravascular Haemolytic Anaemia, cells are lysed in the blood vessels
Answer
  • True
  • False

Question 3

Question
Why is Intravascular H.A so dangerous?
Answer
  • Hb dimers form in the blood and block the kidneys
  • R.B.C fragments block capillaries
  • R.B.C's aggregate and block capillaries

Question 4

Question
Renal failure and Heamoglobinurea are caused by...
Answer
  • Intravascular
  • Extravascular

Question 5

Question
What is implicated in Extravascular Haemolytic Anaemia
Answer
  • The spleen
  • The bone marrow
  • The liver

Question 6

Question
In Extravascular, macrophage Fc receptors bind to the RBC's Ig's
Answer
  • True
  • False

Question 7

Question
Once bound, what happens to RBC's in Haemolytic Anaemia
Answer
  • A small portion of RBC membrane in ingested
  • RBC's a phagocytosed
  • Leukocytes bind to RBC's

Question 8

Question
If small portions of RBC membrane is removed, what happens?
Answer
  • Cell becomes spherical and less malleable
  • And is deformed by spleenic machinary

Question 9

Question
Loss of RBC's leads to low glucose in the spleen, which leads to...
Answer
  • Inc haemolysis
  • Fatigue
  • Inc risk of diabetes

Question 10

Question
Reticuloctosis- inc presence of reticulocytes
Answer
  • True
  • False

Question 11

Question
What causes reticulocytosis?
Answer
  • The body trying to replace lost R.B.C's but can't keep up production
  • The damaged R.B.Cs degenerate into reticulocytes
  • The lymphocytes attack R.B.Cs, making them degenerate into reticulocytes

Question 12

Question
In Drug Induced Haemolytic Anaemia, what happens?
Answer
  • Drug induced antibodies cross react
  • Drug specific antibodies cross react
  • Drugs cause R.B.C's to aggregate

Question 13

Question
Haemolytic Anaemias can be caused by physical stress....
Answer
  • Caused by heart valve turbulence
  • Damage from fibrin strands

Question 14

Question
March Haemoglobinurea is damge to RBC's in small foot bones due to prolonged marching/running
Answer
  • True
  • False

Question 15

Question
Infections can cause H.A by altering R.B.C morphology
Answer
  • True
  • False

Question 16

Question
What's the difference between Immune and Autoimmune Haemolytic Anaemia?
Answer
  • Immune - Antibodies react with own RBC's Autoimmune - Antibodies react with transfused RBC's
  • Autoimmune - Antibodies react with own RBC's Immune- Antibodies react with transfused RBC's

Question 17

Question
In some cases, an RBC transfusion can lead to degredation of the original RBC's
Answer
  • True
  • False

Question 18

Question
Name two types of Inherited Haemolytic Anaemia
Answer
  • Sickel Cell Anaemia
  • Thalassaemia

Question 19

Question
Hereditary Spherocytosis is caused by an abnormal membrane causing Spherical R.B.C's
Answer
  • True
  • False
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