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sana with a rash&easy bruising

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Medicine Mind Map on sana with a rash&easy bruising, created by yasmin alkhatib on 14/05/2017.
yasmin alkhatib
Mind Map by yasmin alkhatib, updated more than 1 year ago
yasmin alkhatib
Created by yasmin alkhatib about 7 years ago
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Resource summary

sana with a rash&easy bruising
  1. cuases of non itchy rash
    1. leprosy
      1. measles
        1. rubella
          1. erysipelas
            1. zinc deficiency
            2. platelets
              1. thrombopoiesis
                1. hemocytoblast
                  1. megakryoblast
                    1. promegakaryocyte
                      1. megakaryocyte
                        1. platlets
                          1. fragment into
                    2. stimulated by
                      1. MGDF
                        1. IL-6
                          1. GMCSF
                        2. life span 8-12 days
                          1. function
                            1. hemostasis
                              1. involoves
                                1. clotting factors
                                  1. endothelium
                                    1. NO, PGI2
                                      1. VWF
                                        1. makes the extracellular collagen more sticky
                                    2. prevention of blood loss
                                      1. when a blood vessel is injured
                                        1. 1) vascular constriction
                                          1. neurogenic reflex
                                            1. myogenic conctriction
                                            2. 2) formation of platelet plug
                                              1. primary plug
                                              2. 3) formation of blood clot
                                                1. secondary plug
                                          2. TH2
                                            1. alpha& delta granules
                                              1. attract more platlets
                                            2. bleeding disorders
                                              1. platelets
                                                1. function
                                                  1. bernard soulier disease
                                                    1. defficiency in VWF receptors ( glycoprotein 1B)
                                                    2. glannzman throbasthenia
                                                      1. prevent the formation of ThA
                                                    3. number
                                                      1. thrombocytopenia
                                                        1. increased destruction
                                                          1. immune thrombocytopenic purpura
                                                            1. Chronic ITP
                                                              1. adults
                                                                1. secondary causes
                                                                  1. HIV
                                                                    1. Epstein-Barr virus
                                                                    2. 6 months of more
                                                                    3. Acute ITP
                                                                      1. children
                                                                        1. viral antigens
                                                                          1. less than 6 minths
                                                                          2. diagnosis by exclusion
                                                                            1. Autoimmune disease
                                                                              1. production of IgG against platelet antigens
                                                                              2. signs and symptoms
                                                                                1. easy bruising
                                                                                    1. petechiae
                                                                                      1. less than 3 mm
                                                                                      2. purpura
                                                                                        1. 1 cm
                                                                                        2. ecchymosis
                                                                                          1. over 1 cm
                                                                                        3. blood in urine and stool
                                                                                          1. heavy menstrual flow
                                                                                            1. bleeding from the gums and nose
                                                                                            2. treament
                                                                                              1. pharmalogical
                                                                                                1. glucocorticods
                                                                                                  1. side effects
                                                                                                    1. hypertension
                                                                                                      1. facial swelling
                                                                                                        1. osteoprosis
                                                                                                          1. folliculities
                                                                                                        2. IV IgG
                                                                                                          1. side effects
                                                                                                            1. vomiting
                                                                                                              1. kidney failure
                                                                                                            2. Thrombopoietin receptor agonists
                                                                                                              1. Rituximab
                                                                                                                1. Anti-(Rh)D
                                                                                                                2. surgical
                                                                                                                  1. splenctomy
                                                                                                                    1. causes
                                                                                                                      1. ruptured spleen
                                                                                                                        1. cancer
                                                                                                                          1. blood disorders
                                                                                                                            1. enlarged spleen
                                                                                                                            2. complications
                                                                                                                              1. postsplenctomy sepsis
                                                                                                                                1. infections
                                                                                                                                2. Laparoscopic surgery
                                                                                                                                  1. open surgery
                                                                                                                              2. stages
                                                                                                                                1. minor normal life style
                                                                                                                                  1. moderate troublesome life style
                                                                                                                                    1. severe lifethreatening
                                                                                                                                      1. internal bleedings
                                                                                                                                  2. disseminated intravascular coagulopathy
                                                                                                                                    1. medical emergency
                                                                                                                                    2. heparin induced thrombocytopenia
                                                                                                                                      1. thrombotic thrombocytopenic purpura
                                                                                                                                      2. decreased production
                                                                                                                                        1. leukemia
                                                                                                                                          1. aplastic anemia
                                                                                                                                            1. megaloblastic anemia
                                                                                                                                      3. clotting factors
                                                                                                                                        1. inherited
                                                                                                                                          1. hemophilia
                                                                                                                                            1. X linked
                                                                                                                                              1. B
                                                                                                                                                1. factor 9 deficiency
                                                                                                                                                2. A
                                                                                                                                                  1. factor 8 deficiency
                                                                                                                                                  2. PTT elevated
                                                                                                                                                  3. Von Willbrand disease
                                                                                                                                                    1. Autosomal dominant
                                                                                                                                                      1. absence of VWF
                                                                                                                                                        1. PTT and bleeding time elevated
                                                                                                                                                      2. acquired
                                                                                                                                                        1. Vit K deficiency
                                                                                                                                                          1. PT & PTT elevated
                                                                                                                                                          2. liver disease
                                                                                                                                                            1. deficiency of clotting factors
                                                                                                                                                        2. invstigations
                                                                                                                                                          1. PT
                                                                                                                                                            1. extrinsic & common pathway
                                                                                                                                                              1. 12-14 sec
                                                                                                                                                            2. PTT
                                                                                                                                                              1. intrinsic and common pathway
                                                                                                                                                                1. 24-35 sec
                                                                                                                                                              2. bleeding time
                                                                                                                                                                1. 2-7 minutes
                                                                                                                                                                2. CBC
                                                                                                                                                                  1. platelet morphology
                                                                                                                                                                    1. platelet count
                                                                                                                                                                      1. 150,000- 450,000 cells\mm3
                                                                                                                                                                  2. blood vessels
                                                                                                                                                                    1. septic vasculitis
                                                                                                                                                                      1. herles danlos disorder
                                                                                                                                                                        1. henoc schonlein syndrome
                                                                                                                                                                        2. history taking
                                                                                                                                                                          1. alchohol
                                                                                                                                                                            1. family history
                                                                                                                                                                              1. medication
                                                                                                                                                                                1. aspirin and NSAIDS

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