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6048952
Th1L06 Intermediate Filaments
Description
Medicine Y1 (Theme 1 | Cells and organelles) Mind Map on Th1L06 Intermediate Filaments, created by Emma Allde on 16/08/2016.
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medicine y1
theme 1 | cells and organelles
Mind Map by
Emma Allde
, updated more than 1 year ago
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Emma Allde
over 7 years ago
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Emma Allde
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Resource summary
Th1L06 Intermediate Filaments
structure
polymer of individual intermediate filament proteins
Formation
(1) intermediate filament protein (monomer) forms a helical dimer
(2) two dimers combine to form a tetrameter
(the fundamental units of the IF)
(3) tetramers link in a staggered formation and end-to-end to form the filament
10nm in diameter
visible by electro microscope
not dynamic
functions
anchor cells at some cell junctions
from a meshwork around the cell nucleus to hold it in place
support nuclear structure
Stabilise the shape of axons
Annotations:
NB: so do MTs
act as diagnostic tools to identify foreign cells as they are expressed differently based on their different locations (e.g. cancer)
common types
keratin, vimentin, glial fibriallary acidic protein, neurofilamin
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