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409241
Tyrosine Kinase
Description
Year 2 Quiz on Tyrosine Kinase, created by gina_evans0312 on 02/12/2013.
No tags specified
cell signalling and cancer
oncogenes
year 2
Quiz by
gina_evans0312
, updated more than 1 year ago
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Created by
gina_evans0312
almost 11 years ago
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Resource summary
Question 1
Question
When the ligand has bound, what moleucle forms?
Answer
A homodimer
A heterodimer within the T.K family
A heterotrimer within the T.K family
A homotrimer
Question 2
Question
What is found in the active site that inhibits activity?
Answer
A pseudosubstrate
An activation lip
A hydrophobic core that must be exposed
Question 3
Question
How do you activate the active site?
Answer
Phosphorylation
Acetylation
Methylation
Question 4
Question
Which residues of tyrosine kinase are modified?
Answer
Tyrosine
Serine
Threonine
Question 5
Question
What domain is required to bind to an activated Tyrosine Kinase?
Answer
Sh2
Sh4
SH3
Question 6
Question
How large is an SH2 domain?
Answer
100 residues
50 residues
25 residues
Question 7
Question
How many pockets are there in SH2?
Answer
1
2
3
Question 8
Question
How does a specific molecule know where to dock on a tyrosine kinase receptor?
Answer
The sequence of aa around the modification it binds to
The shape of the protein around the modification it binds to
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