37127077
Description
Mind Map by Jasper McClellan, updated more than 1 year ago
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Created by Jasper McClellan
over 2 years ago
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Exam 2: Meglitinides
- Pharmacokinetics
- Rapid absorption & elimination
- Metabolized in the liver
- Biliary excretion
- Rapid absorption & elimination
- Pharmacological action
- Increase pancreatic insulin production during and after meals
- Increase pancreatic insulin production during and after meals
- Adverse effects
- Hypoglycemia
- Hypoglycemia
- Contraindications
- Renal Impairment
- Hepatic impairment
- Renal Impairment
- Drug Interactions
- Gemfibrozil (Lopid) inhibits metabolism, causing hypoglycemia
- Gemfibrozil (Lopid) inhibits metabolism, causing hypoglycemia
- Nursing Interventions
- LFTs/Cr at baseline
- 2-hr post-prandial glucose
- LFTs/Cr at baseline
- Extra information
- No more than 4 doses per day
- Repaglinide
- Take no more than 30 min before a meal.
- Skipping a dose = Skipping a meal
Add a dose if adding a meal
- No more than 4 doses per day
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