8887388
Description
Flashcards by Victoria Wright, updated more than 1 year ago
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Created by Victoria Wright
over 7 years ago
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| Question | Answer |
| What are the pigment-producing bacteria? | Actinomyces israelii; S aureus; P aeruginosa; Serratia marcescens |
| Describe the pigment of the following pigment-producing bacteria. Actinomyces israelii | Yellow "sulfur" granules which are composed of filaments of bacteria Israel has yellow sand. |
| Describe the pigment of the following pigment-producing bacteria. S aureus | Yellow pigment Aureus (Latin) = Gold |
| Describe the pigment of the following pigment-producing bacteria. P aerugiosa | Blue-green pigment (pyocyanin and pyoverdin). Aerugula is green. |
| Describe the pigment of the following pigment-producing bacteria. Serratia marcescents | Red Think red maraschino cherries. |
| What are in vivo biofilm producing bacteria? | S epidermidis, Viridans streptococci (S mutans, S sanguinis), P aeruginosa, Nontypeable (unencapsulated) H influenzae |
| Biofilm from S epidermidis is associated with what? | Catheter and prosthetic device infections |
| Biofilm from Viridans streptococci (S mutans, S sanguinis) is associated with what? | Dental plaques, infective endocarditis |
| Biofilm from P aeruginosa is associated with what? | Respiratory tree colonization in patients with cystic fibrosis, ventilator-associated pneumonia. Contact lens-associated keratitis. |
| Biofilm from Nontypeable (unencapsulated) H influenzae is associated with what? | Otitis media |
| Bacterial Virulence Factors promote what? | Evasion of host immune response. |
| What are Bacterial Virulence Factors? | Protein A, IgA protease, and M protein |
| Bacterial Virulence Factors What does Protein A do? | Binds Fc region of IgG. Prevents opsonization and phagocytosis. Expressed by S aureus. |
| Bacterial Virulence Factors What does IgA protease do? | Enzyme that cleaves IgA, allowing bacteria to adhere to and colonize mucous membranes. Secreted by S pneumoniae, H influenzae, type B, and Neisseria |
| acterial Virulence Factors What does M protein do? | Helps prevent phagocytosis. Expressed by group A streptococci. Shares similar epitopes to human cellular proteins (molecular mimicry); possibly underlines the autoimmune response seen in acute rheumatic fever. |
| Describe Type III secretion system | Also known as "injectisome." Needle-like protein appendage facilitation direct delivery of toxins from certain gram- bacteria (eg Pseudomonas, Salmonella, Shigella, E coli) to eukaryotic host cell. |
| Which bacterial virulence factor is expressed by S aureus? | Protein A |
| Which bacterial virulence factor is secreted by S pneumoniae, H influenzae, type B, and Neisseria? | IgA protease |
| Which bacterial virulence factor is expressed by group A streptococci? | M protein |
| Which bacterial virulence factor shares similar epitopes to human cellular proteins (molecular mimicry)? | M protein |
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