Created by Hannah Shakeshaft
about 8 years ago
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Question | Answer |
Biology of mood disorders and schizophrenia: Objectives | - Identify the major mood disorders that affect otherwise “normal” people - Describe evidence that mood disorders have a biological basis - Describe symptoms of schizophrenia - Describe the evidence supporting the role that biology plays in the manifestation of schizophrenia |
Schizophrenia | Negative Symptoms (flat affect, impoverished thought and speech) Positive Symptoms (hallucinations, delusions, excited motor behaviour) Genetic component (studies - adoptions, family & twin) |
Evidence for biological bases of schizophrenia | The main evidence that schizophrenia has a biological basis is from studies of schizophrenics and their relatives. These studies have highlighted the genetic basis for schizophrenia. |
Structural changes in the brain of schizophrenics | - Enlargement of cerebral ventricles -Reduction in size of amygdala and hippocampus - Basal ganglia abnormalities - left hem (greater activity) - Reduction of activity in frontal lobe - Cerebellum shrinkage |
Neurochemical changes in the brain of schizophrenics | - Abnormally high levels of dopamine - Psychotic effects to amphetamine - Effects of anti-psychotic drugs - Parkinson's disease |
Major Mood Disorders | - Bipolar - Unipolar - MDD - Depression |
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