Created by mcrescent03
over 11 years ago
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Question | Answer |
SFA or P:S ratio on NHDL-C. How was it investigated? | ACE modelling 1. adjusted age & BMI 2. adjusted for (1) & adipose SFA 3. adjusted for (1) & adipose P:S ratio |
How much of the variance that could be explained by genetic factors? | 45% |
what are possible genetic and environmental effects on NHDL-C? | physical activity receptors activity and expression age BMI i.e. body fatness gender (hormones) stress? |
order of strength genetic effects on plasma SFA | Arachidic--60% Palmitic--43%==non-sig Stearic--40%==non-sig |
order of strength genetic effects on plasma MUFA | Palmitoleic acid--59%==non-sig Vaccinic acid--55%==non-sig No genetic on levels of Oleic acid |
order of strength genetic effects on plasma n-6 PUFA | All n-6 PUFA Adrenic--66% LA--63% AA--61% DGLA--54% GLA--52% |
order of strength genetic effects on plasma n-3 PUFA | DHA; 22:6n-3--65% EPA; 20:5n-3--55% Non sig genetic effect ALA--48% |
define heritability | h2=genetic variance/phenotypic variance Ratio of phenotypic variance that can be attributed to genotypic variance |
How much genetic effect there were on FA levels in adipose tissue? | 60% stearic acid 63% arachidonic acid |
is believed to have sig influence on NHDL-C. what is it? | dietary SFA |
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