968070
Question 1
Question
A morphogen:
Answer
-
Is not expressed from a localised source in the embryo
-
Does not form a concentration gradient
-
Is not a signalling molecule
-
Specifies cell fates according to its concentration
Question 2
Question
Bicoid mRNA is tightly localised to the posterior end of the egg.
Answer
- True
- False
Question 3
Question
Which of the following is not an example of induction?
Answer
-
Xenopus animal cap assay
-
Homologous recombination
-
Anchor cell signalling to vulval precursors in the C.elegans embryo
Question 4
Question
In mosaic development, isolated cells are able to develop without external signalling.
Answer
- True
- False
Question 5
Question
Somites give rise to which of the following...? (Multiple answers)
Answer
-
Neural tube
-
Skeletal muscle
-
Notocord
-
Dermis
-
Glia
Question 6
Question
MyoD is sufficient to direct muscle development when transfected into non-muscle cells
Answer
- True
- False
Question 7
Question
Reverse genetics uses the mutant phenotype as a starting point
Answer
- True
- False
Question 8
Question
Which of the following are gain of function mutations...?
Answer
-
Amorph
-
Antimorph
-
Neomorph
-
Hypomorph
-
Hypermorph
Question 9
Question
Kit and Steel are in the same gene
Answer
- True
- False
Question 10
Question
Which of the following is the ligand-receptor pair Kit and Steel responsible for the normal development of...? (Multiple answers)
Answer
-
Melanoblasts
-
Keratinocytes
-
Germ cells
-
Fibrocytes
-
Megakaryocytes
-
Haematopoietic stem cells
Question 11
Question
Which one of the following is the correct Hh pathway sequence?
Answer
-
Hh ---| Ptc ---| Smo --> Ci ---> wg
-
Hh ---| Smo --> Ptc --> Ci ---| wg
-
wg ---> Ci ---> Ptc ---| Smo ---| Hh
-
wg ---| Smo ---| Ptc ---> Ci ---> Hh
Question 12
Question
Barchyury codes for a transcription factor responsible for the development of which germ layer?
Answer
-
Mesoderm
-
Ectoderm
-
Endoderm
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