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652426
Jaundice
Description
Aetiology Pathophysiology Clinical Features Biochemical Tests
No tags specified
haem/biochem
haem/biochem
undergraduate
Quiz by
Sophie Barrett
, updated more than 1 year ago
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Created by
Sophie Barrett
over 10 years ago
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Resource summary
Question 1
Question
Jaundice is characterised by a yellow discolouration of the skin and sclera.
Answer
True
False
Question 2
Question
Which of the following best describes the cause of the colour change seen in jaundice patients.
Answer
Too little bilirubin in the skin.
Hyperbiliruinaemia
Bilirubin getting trapped in the skin and not metabolised.
Question 3
Question
Bilirubin is derived from tetrapyrole prosthetic group found in lymphocytes.
Answer
True
False
Question 4
Question
Which of the following are the 3 main causes of why bilirubin levels may rise in blood?
Answer
Haemolysis of red blood cells.
Bilirubin in prescription medications.
Failure of the conjugating mechanism.
Obstruction in the biliary system.
Question 5
Question
Increased bilirubin production as a result of haemolysis gives...
Answer
...a predominantly unconjugated hyperbilirubinaemia.
...a predominantly unconjugated hypobilirubinaemia.
...a predominantly conjugated hyperbilirubinaemia.
...a predominantly conjugated hypobilirubinaemia.
Question 6
Question
Phototherapy should be offered to babies with jaundice if their bilirubin level approaches:
Answer
>200 microlitres per litre.
>40 microlitres per litre.
>300 microlitres per litre.
>100 millilitres per litre.
Question 7
Question
Which of the following best describes the effect of a complete blockage of the bile duct by a gallstone?
Answer
Bilirubin and alkaline phosphatae are raised. Little or no urobilinogen in the urine and the stools will be pale.
Bilirubin is raised and hence, the stools are dark.
Bilirubin urobilinogen are raised, with pale stools and urine.
Question 8
Question
Bilirubin is partly digested by gut bacteria to produce stercobilinogen - this is partly reabsorbed and re-excreted in the urine as urobilinogen.
Answer
True
False
Question 9
Question
Unconjugated bilirubin is normally bound to albumin, but is water-soluble.
Answer
True
False
Question 10
Question
Which 2 of the following are the most common causes of jaundice in adults?
Answer
Paracetamol Poisoning
Viral Hepatitis
Excessive Alcohol Consumption.
Secondary Neoplasm in the Liver
Question 11
Question
A more unusual cause of jaundice is seen in neonates that have...
Answer
been born more than 3 weeks premature.
an alpha 1 - antitrypsin defiency (Wilson's Disease).
been born to a mother who drunk excessive amounts of alcool throughout pregnancy.
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