Cholinergics and Anticholinergics

Description

Pharmacology - Bio 528
thomasina413
Quiz by thomasina413, updated more than 1 year ago
thomasina413
Created by thomasina413 over 10 years ago
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Resource summary

Question 1

Question
ACh is released from the terminal of each of the following neurons EXCEPT:
Answer
  • sympathetic preganglionic neuron innervating the adrenal medulla
  • sympathetic postganglionic neuron innervating the GI tract
  • parasympathetic postganglionic neuron innervating the pupil of the eye
  • motor nerve innervating skeletal muscle

Question 2

Question
Postsynaptic nicotinic receptors are found at each of the following sites EXCEPT:
Answer
  • adrenal medulla
  • sinoatrial node
  • autonomic ganglia
  • skeletal muscle motor end-plate

Question 3

Question
Another name for the sympathetic nervous system outflow is the...
Answer
  • thoracolumbar outflow
  • craniosacral outflow
  • somatic outflow
  • autonomic outflow

Question 4

Question
You would MOST AVOID administering which of the following drugs to the patient taking an MAO inhibitor?
Answer
  • meperidine
  • ephedrine
  • halothane
  • propranolol

Question 5

Question
Release of neurotransmitter requires the entry of what substance into the nerve terminal?
Answer
  • sodium
  • potassium
  • magnesium
  • calcium

Question 6

Question
Which of the following is the correct pairing for sweat glands (division / neurotransmitter)?
Answer
  • sympathetic - norepinephrine
  • sympathetic - acetylcholine
  • parasympathetic - norepinephrine
  • parasympathetic - acetylcholine

Question 7

Question
Side effects of cholinesterase inhibitors include each of the following EXCEPT:
Answer
  • bradycardia
  • increased salivation
  • bronchoconstriction
  • mydriasis

Question 8

Question
You would avoid which agent if the patient w/ glaucoma is being treated with echothiophate?
Answer
  • remifentanyl
  • thiopental
  • mivacurium
  • edrophonium

Question 9

Question
A farmer who one hour ago was spraying his crops with organophosphate insecticide complains of abdominal cramps, muscle weakness, and blurred vision. He is wheezing and bradycardic. Treatment of this condition might reasonably include each of the following agents EXCEPT:
Answer
  • physiostigmine
  • atropine
  • diazepam
  • pralidoxime

Question 10

Question
Nerves that conduct the action potential the fastest are:
Answer
  • myelinated and have small diameter
  • myelinated and have large diameter
  • unmyelinated and have small diameter
  • unmyelinated and have large diameter

Question 11

Question
Signs and symptoms of the anticholinergic syndrome include:
Answer
  • excessive salivation
  • bradycardia
  • excessive sweating
  • mania and hallucinations

Question 12

Question
Which second messenger promotes bronchoconstriction?
Answer
  • cGMP
  • inositol triphosphate (IP3)
  • cAMP
  • calmodulin

Question 13

Question
Which of the following agents produces bronchodilation because of its antimuscarinic actions?
Answer
  • sodium nitroprusside
  • terbutaline
  • aminophylline
  • ipratropium

Question 14

Question
Which of the following agents produces the greatest increase in HR?
Answer
  • scopolamine
  • glycopyrrolate
  • atropine
  • pilocarpine

Question 15

Question
You want to protect the patient from excessive salivation. You also want to PROMOTE sedation. Which drug would be used?
Answer
  • glycopyrrolate
  • atropine
  • scopolamine

Question 16

Question
You want to protect the patient from excessive salivation. You also want to AVOID sedation. Which drug would be used?
Answer
  • glycopyrrolate
  • atropine
  • scopolamine

Question 17

Question
Which antisialogogue is LEAST effective at reducing salivation?
Answer
  • glycopyrrolate
  • atropine
  • scopolamine

Question 18

Question
A farmer who one hour ago was spraying his crops with organophosphate insecticide complains of abdominal cramps, muscle weakness, and blurred vision. He is wheezing and bradycardic. What is he suffering from?
Answer
  • anticholinergic overdose
  • cholinergic syndrome or cholinergic crisis
  • anticholinergic syndrome

Question 19

Question
68-year-old patient was given scopolamine preop and atropine with edrophonium to reverse muscle paralysis at the end of the case. In PACU the patient becomes restless, combative and confused. A rash on the upper body is seen. Tachycardia is also present. What is the condition called?
Answer
  • anticholinergic syndrome
  • cholinergic syndrome
  • anticholinesterase inhibitor
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