Question 1
Question
What is the functional unit of the kidney?
Answer
-
glomerulus
-
nephron
-
medulla
-
cortex
Question 2
Question
Which part of the nephron is mainly responsible for regulating the concentration of urine?
Answer
-
Distal tubule
-
Proximal tubule
-
Loop of Henle
-
Collecting duct
Question 3
Question
Which hormone is required for the reabsorption of water in the collecting tubule?
Answer
-
Renin
-
Angiotensin
-
ADH
-
ANP
Question 4
Question
What is the main solute that is reabsorbed in the proximal tubule?
Answer
-
potassium K
-
sodium chloride NaCl
-
hydrogen H
-
urea
Question 5
Question
Which hormones serve to increase blood pressure? Select all.
Answer
-
angiotensin
-
aldosterone
-
Renin
-
ADH
-
epinephrine
-
norepinephrine
Question 6
Question
What is the net outward pressure that influences glomerular filtration?
Answer
-
20 mmHg
-
10 mmHg
-
15 mmHg
-
5 mmHg
Question 7
Question
Which hormone is produced by the nephrons?
Answer
-
Renin
-
ADH
-
ANP
-
Epinephrine
Question 8
Question
Up to __% of renal function can be lost before renal failure is noticeable.
Question 9
Question
60-70% of acute renal failure is caused by which type of failure?
Answer
-
Pre-renal failure
-
Intra-renal failure
-
Post-renal failure
Question 10
Question
Pre-renal failure is caused by what?
Question 11
Question
Check off all possible causes of post-renal failure.
Question 12
Question
Check off all possible causes of intra-renal failure.
Answer
-
Acute tubular necrosis
-
glomerulonephritis
-
pyelonephritis
-
nephrotic syndrome
-
ureteral stricture
-
cardiogenic shock
Question 13
Question
90% of intra-renal failure is caused by which of the following?
Answer
-
Acute tubular necrosis
-
Glomerulonephritis
-
Pyelonephritis
-
Nephrotic syndrome
Question 14
Question
Acute tubular necrosis (intra-renal failure) is caused by which of the following? Select all.
Answer
-
Prolonged renal ischemia from pre-renal failure
-
Exposure to nephrotoxic drugs
-
Intratubular obstruction (e.g. muscle trauma - release of myoglobin)
-
An immunologic disorder causing glomerular inflammation
Question 15
Question
Proteinuria and hematuria, two main symptoms of glomerulonephritis, are caused by what?
Answer
-
Entrapment in the glomerulus of antigen-antibody complexes produced in response to an infection
-
Prolonged renal ischemia from pre-renal failure
-
Nephrotoxic drugs, such as aminoglycoside antibiotics and radiologic contrast media
-
Baroreceptor-mediated activation of the sympathetic nervous system
Question 16
Question
Loss of transport proteins is part of the process of nephrotic syndrome. What is the result of this loss?
Question 17
Question
Pyelonephritis is caused by which of the following?
Question 18
Question
Women and the elderly are at higher risk for which of the following?
Answer
-
Glomerulonephritis
-
Pyelonephritis
-
Acute tubular necrosis
-
Pre-renal failure
Question 19
Question
In which stage of acute renal failure would you expect to see the following: renal flow at 25% of normal, decreased O2 saturation, decreased urine output, and increased Na in urine?
Answer
-
Initiating stage
-
Oliguric-anuric stage
-
Diuretic stage
-
Recovery stage
Question 20
Question
Does increased urine output happen early or late in the process of acute renal failure?
Question 21
Question
Select all signs and symptoms of acute uremia.
Answer
-
Hypokalemia
-
Increased BUN
-
Pruritus
-
Potential anemia
-
Hyperventilation
-
Thrombosis
Question 22
Question
What are the leading causes of chronic renal failure?
Question 23
Question
A patient presents with the following: mild anemia, increased BUN and serum creatinine, and nocturia. This patient is in which stage of chronic renal failure?
Answer
-
Reduced renal reserve
-
Renal insufficiency
-
Renal failure
-
ESRD
Question 24
Question
Hyperkalemia, hypernatremia, and hyperphosphatemia are all signs of which stage of chronic renal failure?
Answer
-
Reduced renal reserve
-
Renal insufficiency
-
Renal failure
-
ESRD
Question 25
Question
Renal osteodystrophies is a clinical manifestation of chronic renal failure. What is the cause of this manifestation?
Answer
-
Impaired vitamin D synthesis
-
Metabolic acidosis
-
Negative nitrogen balance due to high protein breakdown
-
Decreased platelet activity
Question 26
Question
Are thyroid hormones low or high in chronic kidney disease?
Question 27
Question
Select all appropriate therapeutic interventions for a patient with chronic kidney disease.
Answer
-
Supplemental vitamin D
-
High potassium diet
-
ACE inhibitors
-
Dialysis
Question 28
Question
Which symptom is common throughout ALL stages of chronic kidney disease?
Answer
-
Hyperphosphatemia
-
Anemia
-
HTN
-
Hyperkalemia
Question 29
Question
Select all possible causes of decreased pH of the urine.
Answer
-
Diabetes
-
Starvation
-
UTI
-
Consumption of citrus
Question 30
Question
Select all possible causes of a decrease in specific gravity of the urine.
Answer
-
Renal failure
-
Pyelonephritis
-
Dehydration
-
UTI
-
Acute tubular necrosis
-
Excessive fluid intake
Question 31
Question
What are the normal values of urine pH?
Answer
-
4.8-8.0
-
4.0-6.0
-
2.0-3.8
-
6.0-9.0
Question 32
Question
What are the normal ranges of specific gravity of urine?
Answer
-
4.8-8.0
-
1.025-1.032
-
1.0-2.0
-
1.020-1.045
Question 33
Question
What is the normal range of BUN?
Answer
-
10-20 mg/dL
-
10-20 mg/mL
-
15-30 mg/dL
-
20-25 mg/mL
Question 34
Question
What is the normal range of creatinine clearance?
Answer
-
0.7-1.5 mg/dL
-
0.8-2.0 mg/dL
-
0.7-1.0 mg/mL
-
0.5-1.5 mg/mL
Question 35
Question
The rate of _____ clearance is directly proportional to the rate of filtration of water and solutes across the glomerular membrane.
Answer
-
Inulin
-
Creatinine
-
Urea
-
Sodium
Question 36
Question
The GFR is directly related to:
Answer
-
Perfusion pressure in the glomerular capillaries
-
Diffusion rate in the renal cortex
-
Diffusion rate in the renal medulla
-
Glomerular active transport
Question 37
Question
What force(s) creates passive transport of water in the proximal tubule?
Answer
-
Peritubular capillary hydrostatic pressure
-
Peritubular capillary oncotic and osmotic pressures
-
Interstitial hydrostatic pressure
-
Interstitial oncotic and osmotic pressures
Question 38
Question
______ is a hormone synthesized and secreted by the kidneys.
Answer
-
Erythropoietin
-
ADH
-
ANP
-
Aldosterone
Question 39
Question
A patient exhibits symptoms including hematuria with RBC casts and proteinuria exceeding 3-5 g/day, with albumin as the major protein. These data suggests the presence of which disorder?
Answer
-
Cystitis
-
Chronic pyelonephritis
-
Glomerulonephritis
-
Nephrotic syndrome
Question 40
Question
How are glucose and insulin used to treat hyperkalemia associated with acute renal failure?
Answer
-
Glucose has an osmotic effect, which attracts water and sodium, resulting in more dilute blood and a lower potassium concentration.
-
When insulin transports glucose into the cell, it also carries potassium with it.
-
Potassium attaches to receptors on the cell membrane of glucose and is carried into the cell.
-
Increasing insulin causes ketoacidosis, which causes potassium to move into the cell in exchange for hydrogen.