PHSI3012 07-1 Pathogenesis of Atherosclerosis

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PHSI3012 07-1 Pathogenesis of Atherosclerosis
Michael Jardine
Quiz by Michael Jardine, updated more than 1 year ago
Michael Jardine
Created by Michael Jardine over 6 years ago
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Resource summary

Question 1

Question
Label each bit
Answer
  • Monocytes
  • Neutrophils
  • T cells
  • Blood
  • Endothelial cells
  • Intima
  • Internal elastic lamina
  • Media
  • Adventitia

Question 2

Question
Stages of atherosclerotic progression. Put the following in order: [blank_start]____________________[blank_end] >> [blank_start]____________________[blank_end] >> [blank_start]____________________[blank_end] >> [blank_start]____________________[blank_end] >> [blank_start]____________________[blank_end]
Answer
  • Lipoprotein lodgement
  • Lipoprotein aggregation
  • Monocyte transmigration
  • Foam-cell formation
  • Fibrous lesion

Question 3

Question
ACE = ??
Answer
  • Angiotensin Converting Enzyme
  • Angiotensinogen Converting Enzyme
  • Angiotensin II Converting Enzyme
  • Aldosterone Converting Enzyme
  • Androgen Converting Enzyme
  • Adipose Converting Enzyme
  • Adipokine Converting Enzyme

Question 4

Question
ROS = ??
Answer
  • Reactive Oxygen Species
  • Receptive Oxygen Species

Question 5

Question
PON1 = ?? (major antiatherosclerotic part of HDL)
Answer
  • ParaOxoNase 1
  • PosteriOxoNase 1

Question 6

Question
Which Selectin plays a role in atherosclerotic lesions:
Answer
  • E-Selectin
  • P-Selectin
  • Both of the above
  • [none of the above]

Question 7

Question
True or false: Deletion of CD36 REDUCES foam-cell formation.
Answer
  • True
  • False

Question 8

Question
True or false: Deletion of CD36 BLOCKS foam-cell formation.
Answer
  • True
  • False

Question 9

Question
True or false: Deletion of CD36 INCREASES foam-cell formation.
Answer
  • True
  • False
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