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674337
arthroma
Description
biology ocr F212
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a levels
biology f212
biology f212
as level
Mind Map by
louisemaewhite10
, updated more than 1 year ago
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Created by
louisemaewhite10
over 10 years ago
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Resource summary
arthroma
Damage to lining of artery caused by carbon monoxide, hypertension or high levels of LDLS
Blood LDLs pass into the tunica intima and accumulate-stimulate immune responce
Macrophages engulf the LDL in the tunica intima, die and turn into foam cells
Over time a fatty streak forms made of LDL molecules and foam molecules and foam cells (first visible sign of atherosclerosis)
Smooth muscle cells grow around the fatty streak. Smooth muscle cells cause the proteins collagen and elastin to be laid down forming a fibrous cap
LDL's continue to build up behind the fibrous cap eventually forming an arthroma or plaque
The arthroma may burst causing blood clots to form and further increasing the thickness of the fibrous cap
Eventually the lumen becomes narrower and restricts the flow of blood
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