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Diuretics

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Medicine Pharmacology Mind Map on Diuretics, created by Shaima Amanda on 10/01/2014.
Shaima Amanda
Mind Map by Shaima Amanda, updated more than 1 year ago
Shaima Amanda
Created by Shaima Amanda over 10 years ago
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Resource summary

Diuretics
  1. Extra-renal
    1. Renal
      1. Natriuretics/ Saluretics
        1. Loop diuretics
          1. act on thick ascending
            1. Sulfonamides
              1. Frusemide
                1. Torsemide, Bumetanide
                2. Non-sulfonamides
                  1. Ethacrynic acid
                3. Moderate efficacy diuretics
                  1. Thiazide
                    1. Acts on DCT
                      1. Inhibits NaCl reabsorption
                        1. Increase sodium and water excretion
                          1. hypovolemia, hypercalcemia, hypokalemia, alkalosis, hypocholeremia, hypomagnesemia, hyperuricemia
                        2. Antagonist-> probenecid
                          1. Contraindicated during renal insufficiency
                            1. Has diuretic effect, antidiuretic effect, antihypertensive effect, hyperlipidemia, hyperglycemia, hyperuricemia
                            2. Act on diluting segment
                            3. Low efficacy diuretics
                              1. CAI
                                1. ACI-tazolamide
                                2. K retaining
                                  1. AldoSterONE Antagonist
                                    1. SpironolactONE
                                    2. Non-aldosterone antagonist
                                      1. Amiloride
                                        1. Triamterene
                                  2. Osmotic diuretics
                                    1. Mannitol
                                    2. Acidifying diuretics
                                      1. NH4Cl
                                    3. Reduce hypertension
                                      1. Reduce Renal blood flow and GFR
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