Polymerisation

Description

Degree Pharmacy (PH1402 - Cell and Molecular Biology) Mind Map on Polymerisation, created by Has Maj on 02/12/2015.
Has Maj
Mind Map by Has Maj, updated more than 1 year ago
Has Maj
Created by Has Maj over 8 years ago
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Resource summary

Polymerisation
  1. ACTIN FILAMENT
    1. STAGES
      1. 1.) Nucleation (rate determining step)
        1. G actin
        2. 2.) Elongation (Growth Phase)
          1. Begins once oligomer formed (four actin come together)
          2. 3.) Stable State (equilibrium)
            1. f actin formed
          3. Needs lots of ATP
            1. ATP on actin faces - end of the filament
            2. Growth of the filament only occurs on one side (+ side)
            3. MICROTUBULES
              1. Made of alpha and Beta tubulin
                1. To form filaments it uses GTP as an energy source
                  1. The GTP within the between the alpha and beta dimer holds the structure together
                    1. STAGES
                      1. 1.) Lag Phase
                        1. 2.) Elongation
                          1. 3.)Stable State
                          2. Polarised
                            1. Alpha at top, beta at bottom
                          3. INTERMEDIATE FILAMENTS
                            1. TYPES
                              1. Nuclear
                                1. lining of envelope
                                2. Vimentin- Like
                                  1. Epithiliel
                                    1. Hair and Nails
                                    2. Axonal
                                      1. Axons
                                    3. STRUCTURE
                                        1. Unlike Actin and Microtubules, are often permanent structure
                                        2. FORMATION
                                          1. Not Polarised
                                            1. Desmosomes join filament of different cells
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