37126775
Description
Mind Map by Jasper McClellan, updated more than 1 year ago
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Created by Jasper McClellan
almost 2 years ago
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Exam 2: Second-Generation Sulfonylureas
- Nursing interventions
- Intermittent glucose monitoring
- Obtain baseline BUN, Cr, and LFTs
- Continue monitoring
BUN and Cr if over 65
- Intermittent glucose monitoring
- Pharmacological Action
- Stimulates release of
insulin from the pancreas
- Stimulates release of
insulin from the pancreas
- Extra information
- Less effective over time
- Taken 30 minutes before
breakfast
- Less effective over time
- Pharmokinetics
- Excreted through urine
- Metabolized in the liver
- Excreted through urine
- Adverse effects
- Hypoglycemia
- Nausea
- Heartburn
- Photosensitivity
- Hypoglycemia
- Contraindications
- Sulfa allergy
- Hepatic/Renal Impairment
- Pregnancy/Lactation
- Diabetic ketoacidosis
- Sulfa allergy
- Drug interactions
- Beta-blockers (suppress
insulin release)
- Disulfiram-like reaction
- Drugs that can interact to cause hypoglycemia
- sulfonamide antibiotics
- Acute alcohol ingestion
- NSAIDs
- cimetidine (Tagamet)
- sulfonamide antibiotics
- Beta-blockers (suppress
insulin release)
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