1099553
Description
Mind Map by LiberatedOrgan, updated more than 1 year ago
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Created by LiberatedOrgan
almost 10 years ago
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SLE Systemic Lupus Erythematosus
- Fatigue
- Fever
- Foto-sensitivity
- Foto-sensitivity
- Flares
- Weight Gain
- H2O, Na+ retention
- decrease serum albumin
- decrease serum albumin
- H2O, Na+ retention
- GI issues
- weight loss
- weight loss
- Weight Gain
- Classic S/S
- PAIN
- Fever
- Vasculitits
- Autoimmune
- Chronic inflammation, multiple organs
- antinuclear antibodies (ANA) target nuclear self antigens
- Inflammation in an SLE vessel shows activation of
complement and inflammatory cell infiltration.
Complications r/t increased vascular permeability are
systemic, as the name implies, with multiple organs at
in increase risk for damage and disease.
- Serum labs typically show: elevated liver NZs, sed rate,
C-reactive protein and creatinine ratio; heyolytic anemia,
thrombocytopenia, leukopenia.Outcome of SLE flare: Prevent
pancytopenia
- Serum labs typically show: elevated liver NZs, sed rate,
C-reactive protein and creatinine ratio; heyolytic anemia,
thrombocytopenia, leukopenia.Outcome of SLE flare: Prevent
pancytopenia
- Inflammation in an SLE vessel shows activation of
complement and inflammatory cell infiltration.
Complications r/t increased vascular permeability are
systemic, as the name implies, with multiple organs at
in increase risk for damage and disease.
- antinuclear antibodies (ANA) target nuclear self antigens
- abnormal immune function
- etiology unclear; genetic susceptibility
- etiology unclear; genetic susceptibility
- Chronic inflammation, multiple organs
- pericarditis
- glomerulonephritis / lupus nephritis
- hematuria, proteinurea
- hematuria, proteinurea
- keratitis
- rash (erythemia) is often first symptom
- photosensitive acute
cutaneous molar,
"butterfly" rash
- rash (erythemia) is often first symptom
- Raynaud's Phenomenon
- decreased blood flow extremeties
- vasoconstriction =>cold hands & feet
- vasoconstriction =>cold hands & feet
- decreased blood flow extremeties
- Autoimmune
- American College of Rheumatology criteria for SLE diagnosis: SOAP BRAIN MD
- S: Serositis
- O: Oral Ulcers
- A: Arthritis
- P: Photosensitivity
- B: Blood disorders
- R: Renal involvement
- A: Antiuclear Antibodies
- I: Immunologic phenomenon
- N: Neurologic disorder
- M: Malar rash
- D: Discoid rash
- S: Serositis
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