Catecholamine Action

Question	Answer
Basis of Catcholamines	Tyrosine- made into a catechol ring & a modifiable amide base
Noradrenaline- Location	Central nervous system and sympathetic nervous system
Noradrenaline- Action	Generally inhibitory
Noradrenaline- Method of work	Hyperpolarisation
Noradrenaline- Excess	Mania
Noradrenaline- Deficiency	Depression
Dopamine- Location	A central nervous system
Dopamine- Action	Primarily inhibitory
Dopamine- Excess	Schitzophrenia/Psychosis
Dopamine- Deficiency	Parkinsons
Adrenaline- Production	Chromaffin cells in adrenal medulla
Adrenaline- Location	CNS
Adrenaline- Action	Fight or flight response
Hypertension- Catcheolamines	Increased CA's increase vascular tone and blood pressure
CA Production- Tyrosine	Basis of all CA's
CA Production- DOPA	Created from tyrosine using Tyrosine Hydroxylase
CA Production- Dopamine	Produced from DOPA using DOPA decarboxylase
CA Production- Noradrenaline	Created from Dopamine using Dopamine-Beta-Hydroxylase (found in vesicles, where it's stored)
Adrenaline	Created from Noradrenaline using Phenylethanolamine & S-Adenosyl Methionine, and is stored in vesicles

Resource summary

	Created by gina_evans0312 over 10 years ago