Created by gina_evans0312
almost 11 years ago
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Question | Answer |
Growth on Blood Agar plate | Varies Depending on strain |
Beta Haemolytic Strep. Characteristics | Complete haemolysis- celar area around colony |
Alpha Haemolytic Strep | Partial Haemolysis- greenish tinge around colony |
Gamma Strep | No haemolysis |
Lancefield Classification of Strep | Based of cell wall polypeptides (identified using Ab's) |
Lancefield Classifications | A-H & K-U (The corresponding Ag's cause agglutination |
Mild S. Pyogenes Ingections | Impetigo |
Serious S.Pyogenes Infections | Cellulitis, Necratising Fasciitis |
Eipdemiology- Source | Usually exogenous (or unknown) |
Eipdemiology- Mode of Transmission | Contact/Resp. droplets |
Eipdemiology- Host Immunity | M-Protein Antigen confers some protection |
Eipdemiology- Adhesion Factors | Surface F. Proteins, Lipoteichoic Acid |
Eipdemiology- Immune Evasion (M-Protein) | Binds to host proteins, destabilising compliment and deactivating neutrophils |
Eipdemiology- Immune Evasion (Variance) | M-Protein structure is varied in to help evade the immune system |
Eipdemiology- Immune Evasion (Capsule) | Provides low immunogenicity |
Eipdemiology- Immune Evasion (Streptokinase) | Facilitates spread of bacteria |
Eipdemiology- Exotoxins | SPE A, B & C (A&C are superantigens) with all be pyogenic |
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