456557
Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
almost 11 years ago
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| Question | Answer |
| Ensembl- 'Evidenced' Proteins | Proteins that have been found |
| Ensembl- Proposed Proteins | Proteins suspected, but not yet found |
| Ensembl- Consensus Genes | Genes consisting of the most frequent polymorphisms in all known alleles |
| Ensembl- GENSCAN | Used to create consensus sequences |
| Ensembl- CCDS Tag | NCBI, USC, Havana and Ensembl all agree it exists |
| Ensembl- Data Taken from | NCBI, UniProt, Havana and TrEmbl Reference Sequences |
| Ensembl- ENSGxxxxxx | Ensembl Gene ID |
| Ensembl- ENST | Ensemble Transcript ID |
| Ensembl- ENSP/E | Ensemble Peptide/Exon ID |
| Comparisons- Within a single genome | For gene order, regulatory elements, etc |
| Comparisons- Comparing Genomes | Conserved regions, evolutionary links etc |
| Process Transcript | RNA that won't be transcribed into a protein |
| Comparing Genomes- Browsers to Use | NCBI, Ensembl, UCSC |
| API | Database that uses automatic data extraction by other bioinformatics programmes |
| DAS | Database that integrates with other databases to keep it up to date |
| UTR | Untranslated Region |
| Encode Project | Aimed to find every type of functional element in the human genome- completed 2012 |
| Havana (VEGA) | Group who manually edit gene data- accurate and flexible but slow and expensive |
| Ensembl- Red Sq | Speciation event |
| Polymorphis | DNA variation that is present in at least 1% of people |
| SNP | Change in single nucleotide |
| Practical Applications of SNP's- Association Studies | Studies of traits (one of which is known to be genetic) that commonly appear together |
| Practical Applications of SNP's- Disease Diagnosis | SNP's are commonly implicated in genetic diease |
| Practical Applications of SNP's- Population Studies | Useful in genetic/evolutionary studies |
| Practical Applications of SNP's- Pharmacogenetics | The tailoring of drugs to the individual |
| Essential Splice Site SNP | In the first or last two bases of an intron (as this effects splicing) |
| COSMIC Database | Database of somatic cancer causing SNP's |
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