Bone Pathology

Description

a quick covering of simple bone pathology
Justin Veazey
Flashcards by Justin Veazey, updated more than 1 year ago
Justin Veazey
Created by Justin Veazey almost 10 years ago
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Resource summary

Question Answer
Which homeostasis is Bone commonly associated with? Ca Homeostasis
What kind of Tissue is Bone? Bone: Specialized connective tissue
Osteoid definition Cells & organic extra-cellular matrix (Glycoproteins/collagen fibers)
What is A? A-Osteocytes (B-Calcified cartilage 1-Osteoblasts)
What is B? B- Calcified cartilage
What is Intramembranous ossification? Ossification within 'membranes' of condensed primitive mesenchymal tissue [ex: Flat bones of the Skull]
Endochondral ossificaiton Ossification from a Cartilaginous model (hyaline) [Majority of bones; limbs, vertebral column, pelvis, base of the skull]
What are the common layer names seen in endochondrial ossification? (bonus for cell names assoicated) Resting (Osteyocytes/Bone) Proliferative Hypertropic Cartilage(Osteoblasts)
What is Chondrodysplasia? Breed-associated/hereditary Commonly: Dogs Cattle Sheep Altered Interstitial growth of cartilage (membranous appositional growth is the same)
What is this an example of? Congenital lethal Chondrodysplasia
What is "Micromelic achondroplasia"? Stubby legs! (reduced growth in bones)
What is Cerico-vertebral stenotic myelopathy's common name? (and what is it) Wobbler's syndrome Localized skeletal dysplasia (common in horses & Large Dogs)
What is this an Example of? Wobbler's syndrome [Cervico-vertebral stenotic myelopathy]
What is Osteopetrosis? Inherited disease caused by osteoclast failure to reabsorb the primary spongiosa [Petro- think rock hard]
What Vitamins have effects on Bone development? Vitamin: C, D
What is 'Rickets'? Metabolic disease Mostly effects young
What is the most common cause of Rickets? Rickets is most commonly associated with; Vitamin D/Phosphorus Deficiency (includes lack of sunlight exposure)
Fibrous Osteodystrophy Bone Disease: Extensive bone resorption/replacement by fibrous connective tissue - Poorly mineralized immature bone
Which species is Fibrous Osteodystrophy commonly seen in? Fibrous Osteodystrophy: Horses, cats, dogs, Pigs
Characteristics of Primary Hyperparathyroidism? -Usually associated with functional parathyroid adenomas in dogs -Affected animals exhibit marked hypercalcemia and hypophosphatemia -Lesions may include FO: Thyroid C-cell hyperplasia; hypercalcemic nephropathy (nephrocalcinosis) and metastatic mineralization
Characteristics of Secondary hyperparathyroidism? 1.Nutritional- Ca deficiency, P excess, Vitamin D deficiency 2. Renal- P retention
What is this an Example of? Fibrous Osteodystrophy
What is Osteitis/Osteomyelitis? Mostly Aseptic Inflammation (hematogenous route)
What is a common source of osteomyelitis in neonates? Omphalophlebitis is a common source of osteomyelitis in neonates
Where in piglets does Osteomyelitis locate? Vertebral bodies: Piglets localized osteomyelitis infection
What is "Lion Jaw" Lion Jaw: Proliferative disorder confined to flat bones (Skull, mandibles, occipital, temporal)
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