112075
Description
Flashcards by sammi_taylor01, updated more than 1 year ago
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Created by sammi_taylor01
over 11 years ago
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| Question | Answer |
| What is oxygen measured in in oxygen dissociation curves? | partial pressure (kPa) Normal atmospheric pressure is 100kPa, as oxygen counts for 21% of the atmosphere, it's partial pressure would be 21kPa. |
| At low concentrations of oxygen, why is it harder for the molecule to load oxygen? | Due to the four polypeptide chains being so close together |
| Once the first molecule of O2 is loaded.. | It is easier for the other three O2 molecules to be absorbed by the haem group. |
| If haemoglobin has a lot of oxygen it is called.. Similarly for when it doesn't have a lot of oxygen it's called.. | 1-saturated 2- unsaturated |
| What causes the shape of different haemoglobin molecules change? | Due to different conditions/environments. |
| The further to the left the dissociation curve... | The higher it's affinity, therefore the more readily it loads oxygen but the less easily it releases oxygen. |
| The further to the right the dissociation curve... | The lower the affinity for oxygen and therefore the less easily it loads oxygen but the more readily it releases it to respiring tissues. |
| What effect does the presence of carbon dioxide have on the affinity for oxygen? | Increased carbon dioxide concentrations decreases the molecules affinity for oxygen, therefore the less readily it loads oxygen but the more readily unloads. |
| In the lungs what is the dissociation for oxygen? | High affinity due to the low concentrations of CO2 therefore more easy for the molecule to load oxygen and less readily unloads. |
| In the tissues what is the oxygen dissociation curve like? | Low affinity for oxygen due to the high concentrations of carbon dioxide from the respiring tissues, therefore the more easily it unloads oxygen but less readily loads it. |
| What pH is dissolved carbon dioxide therefore what effect does this have on haemoglobin? | slightly acidic, therefore alters the shape of the molecule so more loosely bound to the oxygen molecules meaning more readily unloads it. |
| Therefore, if low pH changes the shape of the molecule so it releases oxygen more readily, what's the effect of high pH (low concentration of CO2) on the dissociation curve? | High pH alters the shape of the molecule so that it more readily loads the oxygen (it's in high concentration) and less readily unloads it. |
| Describe the statement 'the more active the tissue, the more readily oxygen is unloaded'. | the more active, the more it respires, the more CO2 present, low pH alters shape to low affinity for oxygen, unloads O2 more easily, more O2 available for respiration. |
| In a pregnant woman, where would the babies oxygen dissociation curve be? | To the left, in order for it to pick up oxygen more readily. |
| What is the oxygen dissociation curve of a rat in comparison to a Plaice (that lives on the bottom of the sea). | Rat- low affinity for oxygen as it's active and needs to be able to easily unload oxygen to respiring muscles. Plaice- high affinity as it's in a low oxygen environment and isn't very active, so needs to be able to hold onto oxygen and not release it readily |
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