Enzyme Regulation - Allosteric Enzymes

Description

This quiz assesses the content covered in the notes and flash cards concerning regulation of allosteric enzymes.
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Quiz by daniel.praecox, updated more than 1 year ago More Less
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Created by jill.examtime over 10 years ago
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Copied by daniel.praecox over 10 years ago
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Resource summary

Question 1

Question
Which answer best describes Allosteric Enzymes?
Answer
  • Allosteric enzymes are multi-subunit proteins with one or more active site on each subunit.
  • Allosteric enzymes are multi-subunit proteins with one active site on their subunit.
  • Allosteric enzymes are proteins involved in making and breaking of covalent bonds.

Question 2

Question
What type of graphical representation best describes the activity of Allosteric Enzymes?
Answer
  • Hyperbolic Curve
  • Sigmoidal Curve
  • Linear Regression

Question 3

Question
Allosteric Enzymes are said to behave cooperatively, choose the answer that best describes this behaviour?
Answer
  • The binding of a substrate at one active site induces a conformational change in the protein that is conveyed to other active sites and altering their affinity for substrate molecules.
  • The binding of a substrate at one active site inhibits a conformational change in the protein.
  • The binding of a substrate at one active site induces a conformational change in the protein that is conveyed to other active sites and does not affect the affinity for substrate molecules.

Question 4

Question
Choose the two models that describe Allosteric Enzymes and their effects on proteins?
Answer
  • Concerted Model
  • Ping-Pong Model
  • Michelis-Menten Model
  • Sequential Model

Question 5

Question
Aspartate Carbamoyltransferase ATCase is an example of an allosteric enzyme, What process is it involved in?
Answer
  • Synthesis of Pyrimidine – the formation of N-carbamoylaspartate.
  • Synthesis of Proteins - the formation of Peptide Bonds
  • Synthesis of Purines - the formation of Adenylate

Question 6

Question
What enzyme acts as an allosteric inhibitor in the synthesis of pyrimidines?
Answer
  • Cytosine Triphosphate
  • Adenine Triphosphate
  • Cytosine Diphosphate

Question 7

Question
What intermediate is formed in the synthesis of pyrimidines? What is the role of this intermediate?
Answer
  • Adenosine Tri Phosphate, ATP - Allosteric Inhibitor
  • Adenosine Di Phosphate, ADP - Allosteric Activator
  • Adenosine Tri Phosphate, ATP - Allosteric Activator
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