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Clinical Immunology - Natural Resistance MCQs and Fill in the blanks

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A2 clinical immunology Quiz on Clinical Immunology - Natural Resistance MCQs and Fill in the blanks, created by suyog gurung on 16/06/2022.
suyog gurung
Quiz by suyog gurung, updated more than 1 year ago
suyog gurung
Created by suyog gurung almost 2 years ago
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Resource summary

Question 1

Question
Natural resistance (EP) is a non-specific, innate form of protection:
Answer
  • Yes
  • No

Question 2

Question
The skin and mucous membranes have antimicrobial action:
Answer
  • True
  • Incorrect

Question 3

Question
The complement system is a cellular component of innate immunity:
Answer
  • Yes
  • No

Question 4

Question
NK cells (natural killers) perform intracellular killing of microorganisms and tumor cells:
Answer
  • True
  • incorrect

Question 5

Question
Opsonization facilitates the phagocytosis of bacteria:
Answer
  • Yes
  • No

Question 6

Question
The functions of complement are related to:
Answer
  • Antibody-dependent cellular cytotoxicity (ADCC)
  • Lysis of cells, including bacterial
  • Participation in antigen processing and presentation
  • Opsonization by the C3b particle
  • All answers are correct

Question 7

Question
Where is the presence of lysozyme detected?
Answer
  • In sweat glands
  • In tears and saliva
  • In the skin
  • In the serum and in the mucous secretions of the mucous membranes
  • There is no correct answer

Question 8

Question
Which of the following molecules are acute phase proteins:
Answer
  • C-reactive protein (CRP)
  • Interferon-a
  • Lactoferrin
  • Endotoxin
  • Exotoxin

Question 9

Question
Which of the following cytokines are produced by mononuclear phagocytes:
Answer
  • IL2 and IL4
  • IFN-gamma and IFN-beta
  • TNF-alpha, IL1 and IL6
  • All answers are correct
  • there is no correct answer

Question 10

Question
NK cells (natural killers) perform the following functions:
Answer
  • Activation of complement
  • ADCC
  • Synthesis of antibodies
  • Lysis of virus-infected cells
  • All answers are correct

Question 11

Question
Receptors for the Fc fragment of immunoglobulins have the following cells:
Answer
  • T-lymphocytes
  • Neutrophils
  • Macrophages
  • Dendritic cells
  • All listed

Question 12

Question
In the mucous secretions he most often finds:
Answer
  • IgG
  • IgA
  • IgE
  • IgM
  • IgD

Question 13

Question
The activation of the complement by the alternative route is carried out by:
Answer
  • Bacterial lipopolysaccharides and autoantibodies (eg C3-nephritic factor)
  • C-reactive protein (CRP) and other acute phase proteins
  • Antigen-antibody complexes
  • Peptidoglycan
  • All listed

Question 14

Question
Toll-like receptors (TLRs) are characterized by:
Answer
  • Are located on the surface of T and B lymphocytes
  • Are found on the surface of macrophages and dendritic cells
  • Are detected by binding to antibodies
  • Bind to PAMP (pathogen-associated molecular patterns) structures of bacteria and viruses
  • Activate complete

Question 15

Question
Typical of innate immunity is that:
Answer
  • Is an adaptive form of protection
  • Is inherited and has a non-specific effect
  • Has a memory
  • All answers are correct
  • There is no correct answer

Question 16

Question
How many ways are there to activate the complement system? 1. [blank_start]3[blank_end] List them 1. [blank_start]Classical[blank_end] 2. [blank_start]Alternative[blank_end] 3. [blank_start]Lecithin[blank_end]
Answer
  • 3
  • Classical
  • Alternative
  • Lecithin

Question 17

Question
The following cells are defined as "professional" phagocytes performing effective phagocytosis: 1. [blank_start]Macrophages[blank_end] 2. [blank_start]Neutrophils[blank_end]
Answer
  • Macrophages
  • Neutrophils

Question 18

Question
Humoral factors of natural resistance include: [blank_start]Complement[blank_end] [blank_start]Lysozyme[blank_end] [blank_start]Acute phase proteins[blank_end]
Answer
  • Complement
  • Lysozyme
  • Acute phase proteins

Question 19

Question
Cytokines are [blank_start]PHYSIOLOGICAL MEDIATORS[blank_end] that are synthesized by [blank_start]LYMPHOCYTES[blank_end], [blank_start]FIBROBLASTS[blank_end].
Answer
  • PHYSIOLOGICAL MEDIATORS
  • LYMPHOCYTES
  • FIBROBLASTS

Question 20

Question
The main mechanisms for intracellular killing of bacteria in phagocytosis are [blank_start]2[blank_end] - [blank_start]OXYGEN DEPENDENT[blank_end] , [blank_start]OXYGEN INDEPENDENT[blank_end]
Answer
  • 2
  • OXYGEN DEPENDENT
  • OXYGEN INDEPENDENT

Question 21

Question
C3 particle cleavage? Answer: [blank_start]Central reaction in the complement casca[blank_end][blank_start]de[blank_end]
Answer
  • Central reaction in the complement casca
  • de

Question 22

Question
C5a and C3a particles of complement? Answer: [blank_start]Anaphylatoxins[blank_end]
Answer
  • Anaphylatoxins

Question 23

Question
Ostrophase cytokines? Answer: [blank_start]IL1[blank_end] and [blank_start]IL6[blank_end]
Answer
  • IL1
  • IL6

Question 24

Question
Interferon-alpha and beta? Answer: [blank_start]Have antiviral activity[blank_end]
Answer
  • Have antiviral activity

Question 25

Question
C5-9 complement fractions form? Answer: [blank_start]Membrane attacking complexes[blank_end]
Answer
  • Membrane attacking complexes
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