35292037
Description
Quiz by Esmeralda Espitia, updated more than 1 year ago
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Created by Esmeralda Espitia
almost 3 years ago
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Question 1
Question
1. What genetic process is likely responsible for the occurrence of asthma in only one of a pair of identical twins?
Answer
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a. Epigenetic modifications
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b. Genomic imprinting
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c. Transgenerational inheritance
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d. Methylation
Question 2
Question
2. Prader-Willi syndrome causes a chromosomal defect that is what?
Answer
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a. Initiated by postnatal exposure to a virus
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b. Inherited from the father
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c. Related to maternal alcohol abuse
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d. Transferred from mother to child
Question 3
Question
3. What can a malfunction in DNA methylation lead to?
Answer
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a. Hypothyroidism
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b. Blindness
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c. Cancer
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d. Diabetes mellitus
Question 4
Question
4. Which statement is true regarding the embryonic development of stem cells?
Answer
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a. They are already differentiated.
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b. They are referred to as housekeeping genes.
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c. They already demonstrate DNA sequencing.
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d. They are said to be totipotent.
Question 5
Question
5. When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are over- expressed. What would be the resulting effect on existing cancer?
Answer
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a. Cell death
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b. Metastasis
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c. Remission
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d. Relapse
Question 6
Question
6. What is the difference between DNA sequence mutations and epigenetic modifications?
Answer
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a. DNA sequence mutations can be directly altered.
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b. Leukemia is a result of only DNA sequence mutation.
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c. Epigenetic modifications potentially can be reversed.
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d. No known drug therapies are available for epigenetic modifications.
Question 7
Question
7. Which term refers to the silenced gene of a gene pair?
Answer
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a. Activated
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b. Altered
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c. Mutated
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d. Imprinted
Question 8
Question
8. What is most likely the shape of the face of a child diagnosed with Russell-Silver syndrome?
Answer
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a. Round
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b. Square
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c. Triangular
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d. Elongated
Question 9
Question
9. What are genes responsible for the maintenance of all cells referred to as?
Answer
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a. Universal
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b. Managerial
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c. Housekeeping
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d. Executive
Question 10
Question
10. What is the belief regarding twins who adopt dramatically different lifestyles?
Answer
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a. They may experience very different aging processes.
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b. They will retain very similar methylation patterns.
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c. They will experience identical phenotypes throughout their lifespans.
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d. They may never demonstrate similar DNA sequences of their somatic cells.
Question 11
Question
11. What do hypomethylation and the resulting effect on oncogenes result in?
Answer
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a. A decrease in the activity of the oncogene, thus suppressing cancer development.
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b. A deactivation of MLH1 to halt DNA repair.
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c. An increase in tumor progression from benign to malignant.
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d. An over-expression of microRNA, resulting in tumorigenesis.
Question 12
Question
12. When a chromosome lacking 4 million base pairs is inherited from the mother, the child is at risk for developing which syndrome?
Answer
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a. Prader-Willi
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b. Angelman
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c. Beckwith-Wiedemann
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d. Russell-Silver
Question 13
Question
2. A diagnosis of Angelman syndrome in a child is supported by which assessment findings?(Select all that apply.)
Answer
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a. Small feet and hands
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b. Profound intellectual disability
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c. Obesity
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d. Ataxic gait
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e. History of seizures
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