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Adrenegic Drugs- Pharmacology 4th Year- PMU

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Adrenegic Drugs- Pharmacology 4th Year- PMU
Med Student
Quiz by Med Student , updated more than 1 year ago
Med Student
Created by Med Student about 6 years ago
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Resource summary

Question 1

Question
According to their mechanism of action the adrenergic agonists can be divided in:
Answer
  • direct agonists
  • indirect agonists
  • agonists with mixed mechanism of action
  • natural compounds

Question 2

Question
α1-adrenoceptors are located on:
Answer
  • presynaptic neuronal endings
  • postsynaptic neuronal endings
  • blood vessels
  • iris dilator muscle

Question 3

Question
β1-adrenoceptors are located on:
Answer
  • postsynaptic neuronal endings
  • presynaptic neuronal endings
  • myocardial cells
  • juxtaglomerular apparatus in the kidney

Question 4

Question
β2-adrenoceptors are located on:
Answer
  • postsynaptic neuronal endings
  • bronchial smooth muscles
  • liver
  • uterus (womb)

Question 5

Question
β3-adrenoceptors are located in:
Answer
  • adipose tissue
  • urinary bladder
  • presynaptic neuronal endings
  • bronchial smooth muscles

Question 6

Question
Pharmacological effects of Epinephrine are:
Answer
  • positive chronotropic effect
  • blood pressure elevation
  • bronchial smooth muscles dilation
  • elevated levels of blood sugar

Question 7

Question
Indications for the clinical use of Epinephrine are:
Answer
  • anaphylactic shock
  • hypoglycaemia
  • arrhythmia
  • glaucoma with wide iridocorneal angle

Question 8

Question
Potential adverse drug reactions of Epinephrine are:
Answer
  • hypoglycaemia
  • arrhythmia
  • tremor
  • anxiety and restlessness

Question 9

Question
Clinical indications for prescribing α1-agonists are:
Answer
  • arterial hypotension
  • acute rhinitis
  • asthma attack
  • heart block

Question 10

Question
Pharmacological effects of the selective β2-agonists are:
Answer
  • pupillary dilation
  • bronchial dilation
  • blood pressure elevation
  • relaxation of uterine muscle

Question 11

Question
Which of the following drugs are selective β2-agonists?
Answer
  • lsoprenalini sulfas
  • Orciprenalini sulfas
  • Salbutamol
  • Salmeterol

Question 12

Question
β2-agonists are indicated in:
Answer
  • bronchial asthma
  • digitalis intoxication
  • arterial hypertension
  • threatening abortion

Question 13

Question
Adverse drug reactions of β2-agonists are:
Answer
  • finger tremor
  • bronchial dilatation
  • hyperglycemia
  • tolerance

Question 14

Question
What are the main features of the indirect-acting adrenergic agonists?
Answer
  • stimulation of central nervous system
  • drug tolerance and dependence
  • have no effect on the cardio-vascular system
  • used for treatment of narcolepsy and attention deficiency hyperactivity disorder (ADHD)

Question 15

Question
Clinically desirable interactions can occur between β2-agonists and:(find correct answer)
Answer
  • tricyclic antidepressants
  • inhaled corticosteroids
  • inhaled antimuscarinic drugs
  • beta blockers

Question 16

Question
Mechanisms of action of the presynaptic adrenolytics are:
Answer
  • blockade of the presynaptic α2-receptors
  • activation of the presynaptic α2-receptors
  • conversion to a “false“ neurotransmitter
  • blockade of the phosphodiesterase enzyme

Question 17

Question
Which of the following drugs act as agonists of the presynaptic α2-adrenoceptors?
Answer
  • Salbutamol
  • Clonidini hydrochloridum
  • α-Methyldopum (Dopegyt)
  • Sotalol

Question 18

Question
Pharmacological effects of Clonidin are:
Answer
  • decreased peripheral vascular resistance
  • antihypertensive
  • inhibition of gastric secretion
  • antiarrhythmic

Question 19

Question
Adverse drug reactions of Clonidin are:
Answer
  • Dry mouth
  • Drowsiness and depression
  • Hypertensive attacks following abrupt cessation of treatment
  • CNS stimulation

Question 20

Question
For Methyldopa is true:
Answer
  • has antihypertensive effect
  • it is safe in pregnancy
  • could cause drug-induced parkinsonism
  • used to treat threatening abortion

Question 21

Question
Which of the following drugs are α1-adrenoblockers?
Answer
  • Prazosin
  • Doxazosin
  • Clonidin
  • Chlorpromazin

Question 22

Question
Pharmacological effects of Prazosin are:
Answer
  • dilation of the resistive and capacitive vessels
  • antihypertensive
  • relaxation of the muscles in the prostate and bladder neck
  • hyperglycaemia

Question 23

Question
Adverse drug reactions of α1-adrenoblockers are:
Answer
  • orthostatic collapse
  • hypokalemia
  • fluid retention
  • hypoglycaemia

Question 24

Question
Which of the following drugs are non-selective β-blockers?
Answer
  • Atenolol
  • Pindolol
  • Acebutolol
  • Propranolol

Question 25

Question
Which of the following drugs are selective β1-blockers?
Answer
  • Atenolol
  • Pindolol
  • Propranolol
  • Metoprolol

Question 26

Question
β-blockers are indicated in case of:
Answer
  • hypertension
  • bronchial asthma
  • arrhythmia
  • ischaemic heart disease

Question 27

Question
Pharmacological effects of B-blockers are:
Answer
  • bronchodilation
  • negative inotropic effect
  • positive chronotropic effect
  • negative chronotropic effect

Question 28

Question
β-blocker approved for topical use in treatment of glaucoma is:
Answer
  • Bisoprolol
  • Metoprolol
  • Timolol
  • Propranolol

Question 29

Question
When applied topically in the eye the B-blocker Timolol will:
Answer
  • increase the intraocular pressure
  • decrease the intraocular pressure
  • cause miosis
  • cause mydriasis

Question 30

Question
Potential adverse drug reactions of β-blockers are.
Answer
  • hypoglycaemia
  • bronchoconstriction
  • hyperglycaemia
  • nightmares

Question 31

Question
For long-term treatment with β-blockers is true:
Answer
  • up-regulation of B-adrenergic receptors
  • down-regulation of B-adrenergic receptors
  • the therapy should be ceased abruptly
  • the therapy should not be ceased abruptly
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