Celiac Disease

Description

Mind Map on Celiac Disease, created by wedad attar on 10/02/2018.
wedad attar
Mind Map by wedad attar, updated more than 1 year ago
wedad attar
Created by wedad attar about 6 years ago
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Resource summary

Celiac Disease
  1. Signs & Symptoms
    1. Anemia
      1. Bloating
        1. Fatigue
          1. Diarrhea
            1. Flatulence
              1. Edema
                1. Easy bruising & bleeding
                2. Risk factors
                  1. Family history
                    1. Autoimmune disorder
                      1. Genetic disorders
                        1. Age & Gender
                          1. Ethnicity
                          2. Causes
                            1. Intolerance to gluten
                              1. HLA-DQ2 & DQ8
                                1. Increases risk of disease, but not every person who has this gene will necessarily develop it
                                  1. First-degree relatives have a 40% chance, so they have to do genetic testing
                              2. Pathogenesis & Immunology
                                1. Complications
                                  1. Lactose intolerance
                                    1. Malnutrition
                                      1. Bone loss
                                        1. Osteoporosis
                                          1. Bone density test
                                        2. Infertility
                                          1. Cancer
                                            1. Psychological
                                              1. Anxiety
                                                1. Depression
                                              2. Investigations
                                                1. Serology
                                                  1. IgA TTG
                                                    1. Physical examination
                                                      1. Protuberant and Tympanic abdomen
                                                        1. Weight loss
                                                          1. Orthostatic hypotension
                                                            1. Ascites
                                                              1. Cheilosis and glossitis
                                                                1. Dermatitis herpetiformis
                                                                  1. Ecchymoses
                                                                    1. Evidence of peripheral neuropathy
                                                                      1. Chvostek sign
                                                                      2. Stool exam
                                                                        1. Hematologic tests
                                                                          1. Electrolytes
                                                                            1. Oral tolerance test
                                                                              1. CT enteroclysis
                                                                                1. Endoscopy & biopsy
                                                                                2. Management
                                                                                  1. Gluten-free diet
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