9142942
Description
Flashcards by Victoria Wright, updated more than 1 year ago
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Created by Victoria Wright
over 7 years ago
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| Question | Answer |
| Describe Phase 0 | rapid upstroke and depolarization—voltage-gated Na+ channels open |
| Describe Phase 1 | initial repolarization—inactivation of voltage-gated Na+ channels. Voltage-gated K+ channels begin to open. |
| Describe Phase 2 | plateau—Ca2+ influx through voltage-gated Ca2+ channels balances K+ efflux. Ca2+ influx triggers Ca2+ release from sarcoplasmic reticulum and myocyte contraction. |
| Describe Phase 3 | rapid repolarization—massive K+ efflux due to opening of voltage-gated slow K+ channels and closure of voltage-gated Ca2+ channels. |
| Describe Phase 4 | resting potential—high K+ permeability through K+ channels |
| During Phase 0, there is rapid _________ and _________ | Rapid upstroke and depolarization |
| During Phase 0, voltage-gated NA+ channels _________ | Open |
| During Phase 1, there is _________ of voltage gated Na+ channels. | Inactivation |
| During Phase 1, voltage-gated _________ begin to open | K+ channels |
| During Phase 2, Ca2+ influx through voltage-gated Ca2+ channels balances _________ | K+ efflux |
| During phase 2, _________ influx triggers Ca2+ release from sarcoplasmic reticulum and myocyte contraction. | Ca2+ |
| During phase 2, Ca2+ influx triggers Ca2+ release from _________ _________ and _________ _________ | Sarcoplasmic reticulum and myocyte contraction |
| During phase 3, massive _________ due to opening of voltage-gated slow K+ channels and closure of voltage-gated Ca2+ channels. | K+ efflux |
| During phase 3, massive K+ efflux due to opening of voltage-gated slow K+ channels and closure of _________ | Voltage-gated Ca2+ channels |
| During phase 4, high K+ permeability through _________ | K+ channels |
| Cardiac muscle action potential has a plateau which is due to what? | Cardiac muscle action potential has a plateau, which is due to Ca2+ influx and K+ efflux. |
| Cardiac muscle contraction requires what to induce Ca2+ release from sarcoplasmic reticulum (Ca2+-induced Ca2+ release)? | Cardiac muscle contraction requires Ca2+ influx from ECF to induce Ca2+ release from sarcoplasmic reticulum (Ca2+-induced Ca2+ release). |
| Cardiac muscle contraction requires Ca2+ influx from ECF to induce what? | Cardiac muscle contraction requires Ca2+ influx from ECF to induce Ca2+ release from sarcoplasmic reticulum (Ca2+-induced Ca2+ release). |
| Cardiac myocytes are electrically coupled to each other by what? | Cardiac myocytes are electrically coupled to each other by gap junctions. |
| What are electrically coupled to each other by gap junctions? | Cardiac myocytes are electrically coupled to each other by gap junctions. |
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