PHRM 590 | Pharmacy Practice 1 | Pharmaceutics with Dr. Rao

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PHRM 590 | Pharmacy Practice 1 | Pharmaceutics with Dr. Rao
Austin Thomas
Flashcards by Austin Thomas, updated more than 1 year ago
Austin Thomas
Created by Austin Thomas almost 8 years ago
16
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Question Answer
What is pharmaceutics? Science of dosage form design
Drug? Active chemical of drugs
Dosage form? Formulation Drug with inert ingredients
Examples of Liquids? Solutions, emulsions, suspensions
Examples of Solids? Ointments, creams, pastes, gels
Examples of Semi-Solids? Powders, granules, capsules, tablets
Drug Delivery System? Drug in dosage form intended for a particular purpose or Route of Administration
What are the different Routes of Administration?
What is bioavailability? Unit-less value, often in percent "Fraction of admin dose that reaches physiological activity usually determines onset and extent, AUC determines duration of Action
What are colligative properties? Dependent on total number of species in solution, (solute + solvent) Examples; Boil Point, Freezing Point, Water Vapor, etc..
What happens to blood cells when exposed to the following; hypotonic, isotonic, hypertonic solutions? Hypotonic? solute concentration lowers outside, cells will swell and burst Isotonic? solute concentration is equal Hypertonic? solute concentration is higher inside, cells shrink and shrivel
Determine the number of species a drug molecule will dissociate into; "glucose" Non-Electrolyte **There is only one species here due to only being a solute present in product, also there is not another component to the chemical**
Determine the number of species a drug molecule will dissociate into; "Dextrose" Non-Electrolyte **There is only one species here due to only being a solute present in product, also there is not another component to the chemical**
Determine the number of species a drug molecule will dissociate into; "Urea" Non-Electrolyte **There is only one species here due to only being a solute present in product, also there is not another component to the chemical**
Determine the number of species a drug molecule will dissociate into; "Ranitidine HCl" Weak-Base **There are 3 species here, one is the entire chemical, and then one from the Active Drug itself and then one from the salt**
Determine the number of species a drug molecule will dissociate into; "Homatropine HBr" Weak-Base **There are 3 species here, one is the entire chemical, and then one from the Active Drug itself and then one from the salt**
What is the relationship between MW and molecular size? MW = Total weight of molecule when you add up each component Molecular Size = Size of the molecules Direct Relationship between 2 values
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