Glycogen Phosphorylase Control In The Liver

Question	Answer
Low Glucose- Protein Phosphatase A is bound to	Glycogen phosphorylase- affinity is high
Glucose Low- Glyocgen Phophorylase is	Phosphorylated (hidden and cannot be removed)
Glucose Rises- Glucose Stabilises	Tense form of protein Glycogen phosphorylase A
Glucose Rises- Glycogen Phosphorylase is	Dephosphorylated by protein phosphatase 1
Glucose High- Protein Phosphatase 1	Glycogen synthase is dephosphorylated, and glycogen synthase continues
Glucose High- Glycogen Phosphorylase	Glucose binds to it, causing its tense, inactive form
Why only in the liver?	GLUT2 transporters
GLUT2 Glucose Affinity	Low, so it's only active when blood glucose is high and its a good time to store it
Why Glucokinase?	High glucose Km, so it only functions when blood glucose levels are high

Resource summary

	Created by gina_evans0312 about 10 years ago