Major Histocompatability Complex

Description

Year 2 Flashcards on Major Histocompatability Complex, created by gina_evans0312 on 01/03/2014.
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Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 over 10 years ago
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Resource summary

Question Answer
Polymorphism... Allows recognition of non self proteins/cells
MCHI- Location All nucleated cells
MCHI- Function Display of viral proteins
MCHI- No of Types 3
MCHI- Alpha1 Chain Anchors MCHI to membrane
MCHI- Beta2 Non transmembrane- binds to Alpha1 covalently
MCHI- Alpha 3 and Beta 2 Form an IgG like domain
MCHI- Size of Peptide Presented 8-10 amino acids
MCHII- Location Found solely in professional antigen presenting cells
MCHII- Alpha and Beta Chains Both attach to cell membrane (no B2 domain) with an IgG like domain
Polygenism Many genes availible
Polymorphic Many alleles availbile
MHC is both polymorphic and polygenic Accounting for its variation
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