20558304
Description
Flashcards by Sam Adeyiga, updated more than 1 year ago
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Created by Sam Adeyiga
over 4 years ago
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| Question | Answer |
| Therapeutic range for Carbamazepine: | 4-12 mcg/mL |
| Therapeutic range for Phenytoin: | Total = 10-20 mcg/mL; Free = 1-2 mcg/mL |
| Therapeutic range for Phenobarbital: | 10-40 mcg/mL |
| Therapeutic range for Valproic acid: | 50-100 mcg/mL |
| Long term adverse effects ketogenic diet | 1. kidney stones. 2. increased bone fractures. 3. slowed growth or weight gain. 4. constipation. 5. dehydration. 6. hypercholesterolemia. |
| Adverse effects of VNS | 1. hoarseness 2. cough 3. nausea 4. occasional neck pain, or 5. a tingling sensation during stimulation |
| Serious adverse effects of VNS | 1. infection at the operative site or low-grade fever 2. paralysis of the vagal nerve, left face, or left vocal cord; and 3. urinary retention. |
| AEDS that require renal adjustments [Hint] FEG | FBM EZG GBP |
| AEDS that require renal adjustments [Hint] LLBP | AEDS that require renal adjustments [Hint] LCM LEV BRV PER |
| AEDS that require renal adjustments [Hint] PTZ | PBG TPM ZNS |
| Drugs w/ CYP 450 metabolism HINT: VP-COPP | VPA PER CBZ OXC PHB & PHT |
| Factors that favor successful withdrawal of AED therapy | 1. Patients who are seizure-free for 2 to 4 years 2. Patients who achieve complete seizure control within 1 year of onset. 3. whose seizure onset >2 years old and <35 years old; and 4. Patients that have a normal EEG and neurologic examination. |
| Poor prognostic indicators that may warrant lifelong therapy | 1. high seizure frequency 2. repeated status epilepticus episodes 3. a combination of seizure types 4. development of abnormal mental functioning |
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