13677224
Description
Flashcards by J yadonknow, updated more than 1 year ago
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Created by J yadonknow
over 6 years ago
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| Question | Answer |
| Key components of a reflex arc: | Sense organ Afferent neuron Synapse Efferent neuron Neuro-muscular junction Muscle |
| Reflex Arc (6) | Generator P AP EPSP (and IPSP) AP End-plate P AP |
| MOA (7) | 1. Sense organ generator pt 2. Stim large enough - aff fires AP 3. Aff releases neurot at synapse 4. If neurot bind to R in post-synaptic term then EPSP. 5. AP propagated along Eff 6. epsp at end plate = endplate potential 7. Propagated along muscle generating AP |
| Knee-jerk reflex is an example of a | Mono-synaptic reflex |
| What's the stimulation? | Stretching of the patella tendon |
| What does this cause? | Stretching of extensor muscle |
| How is stretch sensed? | By muscle spindle |
| What does this activate? | Afferent 1a sensory nerve |
| What does this go on to stimulate and how? | 1a releases excitatory neurot from collaterals which synapse onto excitatory neuromuscular junctions |
| What do these do? | Release Ach onto extensor muscle, causes it to contract |
| Where else do collaterals secrete exc neurot? | Onto inhibitory synapses |
| What's the result? | inhibitory neurot released onto excitatory neuromuscular junction Flexo relaxes |
| What's the name of this time of inhibition and excitation? | Reciprocal inhibition |
| How does GABA work? | Inhibitory neurot + Cl- channels Lowers AP |
| Polysynaptic Spinal Reflex stimulus standing on tack | Stimulus + painR in heel |
| MOA flexor contraction | Sensory afferent neuron collaterals synapse with other neurons in the spinal chord Release exc. neurot onto flexor muscle motor neurons Flexor motor neurons release Ach onto muscle Flexor contracts |
| Why need reciprocal inhibition? | Antagonistic pair necessitates reciprocal inhibition |
| Reciprocal inhibition | Sensory afferent also releases exc. neurot onto inhib. synapse Release inhib neurot onto extensor motor neuron |
| Balance | As balance needed, sensory neurons communicate w/ interneurons on opposite side of spinal chord Activates motor neuron innervating extensor and inhibits flexor |
| What is the knee-jerk test used for? | Test if LMN are working |
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