Cognitive Neuroscience - Main Historical Figures and Approaches

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Flashcards on Cognitive Neuroscience - Main Historical Figures and Approaches, created by Savannah Duggan on 05/10/2017.
Savannah Duggan
Flashcards by Savannah Duggan, updated more than 1 year ago
Savannah Duggan
Created by Savannah Duggan over 6 years ago
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Thomas Willis - 1600s, Anne Green revival - 'neurology', Circle of Willis, named many areas and created vital neuro-anatomy resource for 200 years - believed blood held aspects of the soul - we can figure out function by analyzing dysfunction & damage
Franz Joseph Gall - early 1800s - localization (~ 35 faculties located in specific brain structures) - believed brain regions were like muscles, more use = physical growth - phrenology: debunked by Flourens
Marie-Jean-Pierre Flourens - early 1800s, Napolean's scientist - Studied animals and discovered: no cerebellum = no coordination/balance, no cerebral cort = bad perception/movement - aggregate field theory - whole brain contributed to behaviour
John Hughlings Jackson - Late 1800s, clinical neurologist - agreed with aggregate field theory - predicted topographic organization of cerebral cortex by observing muscle movements during seizures
Paul Broca - Late 1800s, Paris - "Tan Man" case: left inferior frontal lobe lesion affected speech generation - example of Localization
Carl Wernicke - Late 1800s, Germany - stroke patient who could freely vocalize nonsense and couldn't understand oral or written language: Lesion in left posterior area affected language comprehension - example of Localization
Hermann Ludwig von Helmholtz - Late 1800s, Germany - figured out electrical currents carried info - dissected sciatic nerve of frog attached to calf muscle; created sensitive timing device/upgraded galvanometer - transmission speeds 24.6-38.4 m/s
Korbinian Brodmann - Early 1900s, Germany - Nissl stain to differentiate areas, analyzed cellular organization of human cortex - IDed 52 areas of cytoarchitectronics
Camillo Golgi - Early 1900s, Italy - Golgi Stain: silver stain 1-3% of neurons, throughout dendrites, soma and axons - Syncytium: believed cells in brain shared continuous network in cytoplasm - shared 1906 physio Nobel with Cajal
Santiago Ramon y Cajal - Early 1900s, Spain - "Father of Modern Neuroscience" - Golgi stains, proposed discrete neurons - info flows primarily one way: from the dendrite to the axonal terminal - shared 1906 in physio Nobel with Golgi
Sir Charles Sherrington - 1932 Nobel prize in physiology - Study of reflexes, characterized the nature of synapses.
Rationalism - Gain knowledge through reasoning, replaced religion among intellectuals - Questioned mental states, morality, society, restricted to assessing via probabilities, induction/deduction, stats - Descartes (dualism) & Liebniz (calculus)
Empiricism - Knowledge from sensory experience - Blank slate, complexities arise with association of simple ideas/info - Thomas Hobbes, John Locke (Tabula Rasa), David Hume, John Stuart Mill - Led to Associationism
Associationism - Mental dev from experiences - Ebbinghaus, Thorndike, Alexander Bain - Bottom-up approach
Hermann Ebbinghaus - Late 1800s, Germany - demonstrated that memory can be investigated experimentally: nonsense syllables, exponential learning and forgetting curves, serial position effect - only studied himself
Edward Thorndike - Early 1900s - "Law of Effect" probability of behaviour following reward, punishment or lack of consequence (operant conditioning) along with Alexander Bain
Behaviourism - strictly objective, only studied observable behaviour (anti-Ebbinghaus) - Watson, Skinner
John B Watson - Early 1900s - transition associationism to behaviourism - Little Albert study: blank slate with brain capabilities to acquire any skill, only difference was experience
B.F. Skinner Strong proponent of behaviourism
Wilder Penfield - 1930s - Stimulated brain with electrical probes during surgery, observed effects - Mapped Jackson's cortices - 'Montreal Procedure' to treat epilepsy, destroyed seizure locus
Donald O. Hebb - Cells that fire together, wire together: Organization of Behaviour, 1949 - brain always active, inputs modify activity - Worked with Penfield
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