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Fluoride

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0 9
Quiz by 0 9, updated more than 1 year ago
0 9
Created by 0 9 almost 8 years ago
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Resource summary

Question 1

Question
Which of these mechanisms allow fluoride to increase the resistance of teeth to acid attack?
Answer
  • Reduce/inhibit enamel dissolving
  • Promoting remineralisation
  • Changing plaque ecology
  • Reducing plaque acid production
  • Increased enamel dissolution

Question 2

Question
What is the acute lethal dose of fluoride?
Answer
  • 32-64mg F / kg body weight
  • 5 g F / kg body weight
  • 32-64g F / kg body weight
  • 5 mg F / kg body weight

Question 3

Question
What is the toxic dose for fluoride?
Answer
  • 5 mg F/ kg body weight
  • 5 g F/ kg body weight
  • 32-64mg F / kg body weight
  • 32-64g F / kg body weight

Question 4

Question
What are some clinical symptoms of fluoride poisoning?
Answer
  • Nausea
  • Diarrhoea
  • Convulsions
  • Cardiac arrhythmias
  • Conjunctivitis

Question 5

Question
Why might acute fluoride poisoning lead to cardiac dysrhythymia?
Answer
  • Hypocalcemia / Hyperkalemia
  • Hypercalcemia / Hypokalemia
  • Hypernatremia / Hyperkalemia
  • Hypercalcemia / Hyponatremia

Question 6

Question
Skeletal fluorosis is sometimes mistaken for...
Answer
  • Arthritis
  • Osteoporosis
  • Parkinson's
  • Huntington's

Question 7

Question
How does fluoride impair enamel formation?
Answer
  • Interferes with the ameloblasts in the early maturation phase leading to imperfect crystals / prisms
  • Interferes with the ameloblasts in the late maturation phase leading to imperfect crystals / prisms
  • Leads to imperfect collagen deposition by the ameloblasts leading to imperfect crystals / prisms
  • Leads to imperfect hydroxyapatite deposition by the odontoblasts leading to imperfect enamel crystals / prisms

Question 8

Question
How does fluoride impair dentin formation?
Answer
  • Leads to impaired random collagen and hydroxyapatite deposition which is more susceptible to caries
  • Leads to impaired random hydroxyapatite deposition which is more susceptible to caries
  • Leads to impaired random collagen deposition which is more susceptible to caries

Question 9

Question
Fluoride _________ mineralisation of bone, leading to heavy irregular mineralisation of bone.
Answer
  • Stimulates
  • Inhibits

Question 10

Question
75-90% of fluoride is absorbed in the
Answer
  • Stomach
  • Duodenum and Upper jejunum
  • Lower jejunum and ileum
  • Duodenum only

Question 11

Question
Fluoride is mostly absorbed by...
Answer
  • Passive diffusion
  • Active transport
  • Facilitated diffusion

Question 12

Question
Maternal and Foetal blood fluoride levels tend to be..
Answer
  • Similar, therefore related.
  • Completely different, therefore unrelated.

Question 13

Question
The three phases of fluoride transport are: 1. Tissue fluid / soft tissue eq[blank_start]uilibration[blank_end] and dilution 2. Hard tissue deposition in tissues with high F [blank_start]affin.[blank_end] 3. [blank_start]Renal[blank_end] clearance of F which not deposited in skeleton
Answer
  • uilibration
  • affinity
  • Renal

Question 14

Question
Fluoride accumulates in the soft tissues.
Answer
  • True
  • False

Question 15

Question
Saliva and Tissue fluid have similar fluoride levels to blood plasma.
Answer
  • True
  • False

Question 16

Question
Why does fluoride have such a high affinity for bone?
Answer
  • It has a high affinity for hydroxyapatite in bone, preferentially forming fluorapatite.
  • It has a high affinity for collagen in bone, preferentially forming fluoridated collagen.
  • It has a high affinity for receptors in bone marrow which allow it to bind readily

Question 17

Question
What is the half life of fluoride in someone who is not frequently exposed to F?
Answer
  • 24 hrs
  • 2 years
  • 12 hrs
  • 1 hr

Question 18

Question
What factors might impact on renal clearance of fluoride?
Answer
  • Dose of fluoride
  • Previous exposure
  • Fluid intake
  • Cirrhosis
  • Half life of fluoride

Question 19

Question
Fluoride interferes with acid production by bacteria. How does it inhibit it?
Answer
  • Inhibits the enolase enzyme involved in glycolysis (which ultimately produces lactic acid)
  • Inhibits the alpha-ketoglutarate enzyme involved in glycolysis (which ultimately produces lactic acid)
  • Inhibits the hexokinase enzyme involved in glycolysis (which ultimately produces lactic acid)

Question 20

Question
Fluoride interferes with extracellular polysaccharide formation
Answer
  • True
  • False

Question 21

Question
Fluoride decreases bacterial intracellular polysaccharide formation and glucose uptake.
Answer
  • True
  • False

Question 22

Question
Fluoride does not affect cariogenicity but does decrease the amount of plaque formation.
Answer
  • True
  • False
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