Gastro-Intestinal Disorders- Clinical Pharmacology 5th Year PMU

Description

Gastro-Intestinal Disorders- Clinical Pharmacology 5th Year PMU
Med Student
Quiz by Med Student , updated more than 1 year ago
Med Student
Created by Med Student over 4 years ago
105
6

Resource summary

Question 1

Question
Which are the main drug groups for treatment of ulcer disease
Answer
  • antacids drugs
  • anti-secretion drugs
  • gastro-duodenal protectors
  • drugs against HP infections

Question 2

Question
Which are non-absorbent antacid drugs
Answer
  • sodium salts
  • calcium salts
  • aluminium salts
  • magnesium salts

Question 3

Question
Which are anti-secretion drugs
Answer
  • Proton pump inhibitors
  • H2-histamine blockers in stomach mucosa
  • M3-cholinergic blockers in stomach mucosa cells
  • COX inhibitors

Question 4

Question
Which drugs are used for eradication of Helicobacter pylori-infections
Answer
  • proton pump inhibitors
  • colloidal bismuthi salts
  • histamine blockers
  • antibacterial drugs

Question 5

Question
Proton pump inhibitors are
Answer
  • Omeprazole
  • Rabeprazole
  • Mizoprostol
  • Lansoprazole

Question 6

Question
Gastrointestinal mucosa protectors are
Answer
  • Sucralphate
  • Misoprostol
  • Probiotics
  • Colloidal bismuths salts

Question 7

Question
Well known drug interactions of proton pump inhibitors are
Answer
  • decreased absorption of some antibiotics as tetracyclines, isoniazid, ciprofloxacin
  • decreased absorption of some other drugs as digoxin, quinidine, theophylline, NSAIDs, warfarin
  • increased absorption of some antibiotics as tetracyclines, isoniazid, ciprofloxacin
  • increased absorption of other drugs as digoxin, quinidine, theophylline, warfarin

Question 8

Question
Drugs contraindicated during pregnancy or breast feedings are
Answer
  • Bismuth salts
  • Misoprostol
  • Proton pump inhibitors
  • Antacid drugs

Question 9

Question
Maintenance therapy is indicated for patients with
Answer
  • complicated chronic ulcer disease with bleeding and perforations
  • concomitant erosive reflux esophagitis or reflux gastritis
  • patients over 50 years of age and concomitant diseases requiring often usage of NSAIDs or other drugs irritating stomach or duodenal mucosa
  • chronic tobacco smokers or people with liver cirrhosis, chronic obstructive lung disease etc.

Question 10

Question
Corrections of dose regimen are recommended for
Answer
  • H2-histamine blockers treatment (Cimetidine or Ranitidine) for patients with liver insufficiency
  • H2-histamine blockers in patients with kidney insufficiency
  • Proton pump inhibitors in patients with liver insufficiency due to prolonged half-life
  • Proton pump inhibitors in patients with kidney insufficiency
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