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550256
Heart Myocytes
Description
An example of a Direct- Effector Linked Pathway in Heart Myocytes. Note: The same neurotransmitter (acetylcholine) causes the opposite effect in skeletal muscle.
No tags specified
cellular pathology
signal transduction pathways
cellular pathology
signal transduction pathways
undergraduate
Mind Map by
Sophie Barrett
, updated more than 1 year ago
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Created by
Sophie Barrett
almost 11 years ago
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Resource summary
Heart Myocytes
Stimulation from parasympathetic nervous system
Acetylcholine acts on metabotropic, muscarinic receptors in the heart
G-Protein is activated
Effector protein is a K+ ion channel (stimulated to open)
K+ ions flow out of the cell (down their concentration gradient)
Increases negativity inside the cell (hyperpolarisation)
Leads to decreased contraction
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