517488
Description
Mind Map by v.djabatey, updated more than 1 year ago
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Created by v.djabatey
almost 11 years ago
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Wilms tumour (nephroblastoma)
- origin= embryonal renal tissue
- commonest renal
tumour of childhood
- > 80% pts present before 5 years old
- rarely seen after 10 years old
- rarely seen after 10 years old
- clinical features
- presentation
- common
- abdo mass
- large
- incidental
finding in
otherwise well
child
- large
- abdo mass
- uncommon
- abdo pain
- anorexia
- anaemia
- haemorrhage
into mass
- haemorrhage
into mass
- haematuria
- hypertension
- abdo pain
- common
- presentation
- Ix
- US +/- CT or MRI
- showing intrinsic renal
mass distorting normal
struc
- envelopes a remnant of normal renal tissue
- envelopes a remnant of normal renal tissue
- characteristic mixed densities visible
- cystic and solid
- cystic and solid
- showing intrinsic renal
mass distorting normal
struc
- staging
to assess
- for distant mets
- usually in lung
- usually in lung
- initial tumour resectability
- function of contralat kidney
- for distant mets
- US +/- CT or MRI
- Mx
- initial chemo fb delayed nephrectomy
- then tumour histologically staged
- then Rx planned
- then Rx planned
- then tumour histologically staged
- radiotherapy
- only for those w/
more advanced
disease
- only for those w/
more advanced
disease
- initial chemo fb delayed nephrectomy
- good prognosis
- > 80% of pts cured
- cure rate for pts w/ mets
@ presentation is > 60%
- > 80% of pts cured
- relapse has poor prognosis
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