Chapter 12: DNA

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Mind Map on Chapter 12: DNA, created by StudyBuddy on 20/12/2013.
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Chapter 12: DNA
  1. Rosalind Franklin
    1. Studied DNA in 1950s using advanced x-ray technology
      1. Obtained detailed image of DNA that hinted at it's 3-D shape
      2. James Watson and Francis Crick
        1. Worked off Franklin's x-ray images and measurements to determine 3-D model with double helix
        2. DNA: Deoxyribose Nucleic Acid
          1. DNA is a polymer made of a long chain of repeated monomers called nucleotides. DNA has a shape of a double helix(spiral)
            1. Replication
              1. In Eukaryotic cells, DNA is folded tightly to fit in the cell. A cell replicates its DNA before the cell divides(Interphase).
                1. Why does the double helix model foe DNA lend itself easily to replication?
                  1. Each strand has all the info needed to make the complementary strand
                  2. Steps in Replication
                    1. 1) Enzymes unzip a molecule of DNA by breaking hydrogen bonds
                      1. 2) Separated strands serve as a template(model) for 2 new complementary strands
                        1. 3) DNA polymerase joins individual nucleotides to produce DNA and proofreads each new strand
                2. Nucleotide
                  1. Phosphate
                    1. Deoxyribose Sugar
                      1. Nitrogenous Base
                        1. Chargaff's Rule
                          1. %A=%T %C=%G
                            1. The Code
                              1. A= Adenine T= Thymine G= Guanine C= Cytosine
                  2. Telomeres - extra repeated sections of DNA at the ends of chromosomes
                    1. Telomeres aren't actual genes
                      1. They protect important genes
                        1. They get shorter as cell ages
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