420109
Description
Mind Map by fandrickb2, updated more than 1 year ago
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Created by fandrickb2
over 10 years ago
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Antiinfective
Drugs
- Bacteriocidal
- Drugs that interfere with the cell wall
- Penecillins, cephalosporins, bacitracin
- Penicillins
- Gram + cocci
- Penicillinase resistant: enzyme produced by staphylococci making it microbe resistant.
- Penicillinase resistant: enzyme produced by staphylococci making it microbe resistant.
- Extended spectrum g+/-: e coli, H influenzae, proteus mirabilis
- ampicillin, amoxocillin: claculanic acid is penicillinase resistant.
- ampicillin, amoxocillin: claculanic acid is penicillinase resistant.
- Gram + cocci
- Cephalosporins:
spectrum varies w each
generation + to more -
- 10% cross hypersensitivity w penicillin
- 10% cross hypersensitivity w penicillin
- Penicillins
- Penecillins, cephalosporins, bacitracin
- Drugs that interfere with the cell membrane
- antifungals: nystatin, ketoconazole, clotrimazole
- antifungals: nystatin, ketoconazole, clotrimazole
- Drugs that interfere with the cell wall
- Bacteriostatic
- drugs that interfere with protein synthesis:
- metronidazole, tetracyclines, clindamycin, erythromycin
- Tetracyclines: broad spectrum (gram +/-)
- bind to calcium: bad for pregnat/breastfeeding women
- ADR: GI upset, stomatitis, superinfection,
photosensitivity, enamel hypoplasia,tooth
staining
- bind to calcium: bad for pregnat/breastfeeding women
- Macrolides: gram + microbes
- used in ppl w penicillin allergies
(clarithromycin & azithromycin common in
dentistry)
- ADR: GI upset , stomatitis, candidiasis
- Interactions: eryth:
bronchodialator (inc theophylline
levels), inc. warfarin effect, dec.
Birth control pill effect
- used in ppl w penicillin allergies
(clarithromycin & azithromycin common in
dentistry)
- Metronidazole: inhibits PRO synthesis
(not normal)
- perio anaerobic infections: NUG/NUP
- avoid alcohol (food, drink, rinses)
- avoid alcohol (food, drink, rinses)
- perio anaerobic infections: NUG/NUP
- Tetracyclines: broad spectrum (gram +/-)
- metronidazole, tetracyclines, clindamycin, erythromycin
- drugs that interfere with protein synthesis:
- Antifolates
- drugs that interfere with nucleic acid synthesis
- sulfa, quinalones (ciprofloxacin & norfloxacin), & antiTB drugs (rifampin & isoniazid)
- Fluoroquinolones: affect bacterial DNA
- avoid elecive dental Tx if TB+
- Dr consult to confirm liver function
- Fluoroquinolones: affect bacterial DNA
- sulfa, quinalones (ciprofloxacin & norfloxacin), & antiTB drugs (rifampin & isoniazid)
- drugs that interfere with nucleic acid synthesis
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