Deep Vein Thrombosis

Pathophysiology
1. Thromus composed of platelets, fibrin and leukocytes develop
2. Venous Stasis
3. Hypercoagulable state (activation of bolo coagulation)
4. vein damage (decreased wall contractility, and valve dysfunction)
Clinical Presentation
1. Edema in Extremity
2. Pain at site
3. Tenderness at site
4. Homans Sign (Pain and resistance to dorsiflexion in foot)
5. Warmth and/or Erythemia
6. Positive Thoracic outlet meneuver in upper extremities
Epidemiology
1. higher in hospitalized patient's by 20-70%
2. 600,000 hospitalized annually
3. Higher in Caucasian and African American than Hispanics and Asians
4. Complicated 1/1,000 pregnancies
Diagnosis
1. D-dimer test
2. Coagulation studies (PT/INR, PTT)
3. Ultrasound doppler studies
Treatment
1. Prophylactic Anticoagulation
2. Endovascular and surgical interventions
3. Physical Activity
4. Compression Stockings
5. Thrombolysis Medications

Resource summary

	Created by Spotlep over 9 years ago

	Copied by Spotlep over 9 years ago