91223
Description
Flashcards by laura.marsland, updated more than 1 year ago
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Created by laura.marsland
about 11 years ago
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| Question | Answer |
| List 3 reasons why blood is considered a connective tissue | 1. It is mesoderm-derived 2. It contains fibres (which are soluble in clotted blood) 3. It has a fluid/semi-fluid matrix |
| Give three possible molecular explanations for the presence of abnormal haemoglobins in a patient’s blood | 1. Production of structurally abnormal haemoglobin molecules due to mutation in globin structural gene 2. Presence of abnormal ratio of subunits due to over or under production of globin subunits 3. Change in post-translational modification of globin sub-units |
| Explain why a patient with anaemia is likely to feel tired | Low haemoglobin is associated with a reduced ability to carry oxygen tissues. Lack of oxygen in tissues reduces aerobic metabolism. Reduced aerobic metabolism means inadequate ATP level to maintain cell function. |
| What happens to carbohydrate eaten in excess of the body's requirement? | Stored as glycogen in the liver and skeletal muscle Converted to fatty acids and stored as triacylglycerols in adipose tissue |
| Give 4 histological features of adipocytes in white adipose tissue | Large lipid droplet (triacylglycerols) filling cell Nucleus pushed to one side Small amount of cytoplasm pushed to one side Small number of mitochondria |
| How are fatty acids transported in the blood? | They are hydrophobic and can only be transported bound to albumin |
| Why does the concentration of fatty acids never exceed 3mM? | Saturation of binding sites on albumin |
| Define axonotmesis | Axon is ruptured but myelin sheath remains in tact |
| Define neurotmesis | Complete severance of axon & myelin sheath of peripheral nerve |
| Define neuropraxia | 'Nerve shock'. Axon & myelin remain in tact but conduction temporarily disrupted |
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