5191744
Description
Flashcards by Amaal Salhieh, updated more than 1 year ago
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Created by Amaal Salhieh
over 8 years ago
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| Question | Answer |
| What is the most common cause of bronchiolitis? | RSV |
| What is the second most common cause of bronchiolitis? | Parainfluenza |
| Bronchiolitis is most common in what group of people? | People less than 2 yo Most common in 1st year of life |
| What season does bronchiolitis peak in? | Winter |
| Treatment for bronchiolitis | Supportive |
| What is the most common cause of acute bronchitis? (general) | Viruses 90% of the time |
| Acute bronchitis affects what age groups? | All age groups |
| What season does acute bronchitis peak in? | Varies, depending on which infectious agent |
| Acute bronchitis treatment | Symptomatic Abx not recommended unless bacterial |
| Croup distinct clinical syndrome | barking cough |
| What is the most common cause of croup? | Parainfluenza |
| What is the second most common cause of croup? | RSV |
| What age group is usually affected by croup? | Between 3 months and 3 years of age Peaks in year 2 |
| Croup diagnosis | Primarily clinical diagnosis "Steeple sign" on xray |
| Croup treatment | Keep child comfortable Take into cool night air or breathe warm mist If severe, dexamethasone (steroid) |
| What is a major protein associated with paramyxoviridae? And what does it do? | F protein (fusion protein) Promotes fusion of viral and host cell membranes Can cause cell-to-cell fusion (syncytia and giant cells) |
| RSV pathogenesis | DIrect invasion of respiratory epithelium (no viremia) induces syncytia formation via F ptn Spreads cell-to-cell, hiding from immune system Immunity is not long-lasting |
| RSV is the most common cause of... | bronchiolitis |
| RSV is the second most common cause of... | croup |
| Parainfluenza virus Pathogenesis | Infects URT Cell lysis and giant cell formation Usually no viremia May spread to lower tract |
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