Drugs

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Medicine Pharmacology Flashcards on Drugs, created by Shaima Amanda on 11/01/2014.
Shaima Amanda
Flashcards by Shaima Amanda, updated more than 1 year ago
Shaima Amanda
Created by Shaima Amanda almost 11 years ago
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1. Cannot be given intravenously or intramuscularly, else it will cause severe hypotension and bradycardia. 2. Cannot cross blood-brain barrier. 3. Contraindicated during asthma, ulcer, hyperthyroidism or bradycardia (Hint: parasympathomimetics) Choline Esters. Examples: acetylcholine and methocholine
1. Treats choline ester overdosage Atropine
1. Can cross blood brain barrier 2. Used in the treatment of glaucoma, and causes miosis and diaphoresis 3. Used as a sialagogue and hair lotion. Pilocarpine
1. Reverses anticholinesterase within 5 minutes and is not a substrate of cholinesterase 2. Used in the diagnosis and treatment of myasthenia gravis. 3. Is an antidote for curare poisoning. Edrophonium
1. Can cross blood brain barrier and is used in the treatment of glaucoma, and reverse mydriatics (just like pilocarpine). 2. Can be taken orally 3. Is used as an antidote in atropine poisoning. Physostigmine
1. Cannot cross blood brain barrier. 2. Is used in the diagnosis and treatment of myasthenia gravis. 3. Causes paralytic ileum and retention of urine. 4. Antidote in Curare poisoning. Neostigmine
1. Organophosphorus. 2. Lipid insoluble. 3. Used in the treatment of glaucoma. 4. Lasts for 3-4 weeks. Ecothiophate
1. Is used as a pre-anesthetic. 2. Causes mydriasis, cytoplegia, loss of light response,decreases sweating, lacrimation and all kinds of secretions and may cause flush. 3. Used to prevent synechiae. Atropine
Used in the treatment of bronchial asthma. Ipratropium
Controls seizures and convulsions Diazepam
Cannot be used during prostatic hyperplasia and closed angle glaucoma as this particular drug increases the intraocular pressure. Atropine
1. Preferred pre-anesthetic drug. 2. Causes sedation and amnesia. 3. Used in the treatment of motion sickness. Hyoscine
Treatment of peptic ulcers and colics. Pirenzepine and telenzepine
Used to reduce nocturnal eneuresis. Emepronium
1. Cannot be taken orally and cannot pass the blood brain barrier. 2. It is used to delay the absorption of drugs given subcutaneously. 3. Causes decongestion, bronchodilation and increases heart rate. Epinephrine
Relaxes the uterus of pregnant women Epinephrine
In the treatment of open angle glaucoma Dipivefrin
Causes hypertension, gangrene,headaches, cerebral hemorrhage, tachycardia, arrythmia, angina, and skeletal muscle tremors. Epinephrine
1. During spinal anesthesia and after sympathectomy. 2. Causes bradycardia, necrosis, sloughing, anxiety and headache. 3. Active mydriasis and contriction of sphincters. Norepinephrine
Used in the treatment of heart failure, septic shock, cardiogenic shock and hemorrhagic shock. Dopamine
Selective D1 receptors Fenoldopam
Affects alpha 1, alpha 2, beta 1 and beta 2 receptors Epinephrine
Mainly affects alpha 1 receptors, and may interact with beta 1 too. Norepinephrine
Interacts with D1 and D2 receptors in small dose, D1, D2, and B1 receptors in moderate dose AND D1, D2, A1 and B1 in high dose. Dopamine
Non-selective Beta agonists. It is used in the treatment of acute heart block. Isoprenaline
Bronchodilatation. Relax wall of GIT, Urinary bladder & Uterus. Skeletal Muscle Tremors. Hyperglycemia. Hyperlipidemia. Epinephrine or Isoprenaline
Selective Beta- 1 agonists Dobutamine
It improves the rate of contractility with minimal tachycardia, and is used in the treatment of cardiogenic shock and heart blocks. Dobutamine
Used as a uterine relaxant during abortion, premature labor and dysmenorrhea. Ritodrine
Drugs that decrease the intraocular pressure while causing mydriasis, bronchodilation, bradycardia, constriction of sphincters, relieves nasal congestion and most importantly in Attention-deficit hyperkinetic disorder. Ephedrine, Amphetamine, Methylphenidate
Selective alpha 1 agonists Vasopressin
Non selective alpha 1 and alpha 2 agonists Phenotolamine
Selective alpha 1 blocker Prazosine
Treat Benign Prostatic hyperplasia Doxazosin. More effective--> Tamsulosin.
Treat angina, arrythmia, heart failure and hypertension. Beta blockers
Beta blocker that is used to treat glaucoma Timolol
Beta blocker that is used to treat migraines Propanolol
Selective Beta 2 blocker that is not used clinically Butoxamine
Ultrashort acting B-blocker. T-1/2 is 5 minutes Esmolol
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