Bilateral vestibular schwannomas
A first-degree relative with NF2 AND Unilateral vestibular schwannoma OR Any two of: meningioma, schwannoma, glioma, neurofibroma, posterior subcapsular lenticular opacities *
Unilateral vestibular schwannoma AND any two of: meningioma, schwannoma, glioma, neurofibroma, posterior subcapsular lenticular opacities *
Multiple meningiomas AND Unilateral vestibular schwannoma OR Any two of: schwannoma, glioma, neurofibroma, cataract

Genetic testing:

De novo - Look at tumour DNA - has there been knock-out of the two NF2 alleles
Inherited - look at leukocyte DNA

	Created by Ellie Quinn over 10 years ago

Note on Neurofibromatosis 2, created by Ellie Quinn on 30/05/2014.