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BSc (Hons) Biology Quiz on Cancer & Autoimmune Disease: Quiz the Sixth, created by Sami-Jaine on 09/05/2013.

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Cancer & Autoimmune Disease: Quiz the Sixth

Question 1 of 12

1

Most cancers could be prevented.

Select one of the following:

  • True

  • False

Explanation

Question 2 of 12

1

Which 3 of the following abberations cause a proto-oncogene to mutate into an oncogene?

Select one or more of the following:

  • Amplification

  • Translocation

  • Point Mutation

  • Addition

Explanation

Question 3 of 12

1

BCR-ABL is an oncogene caused by the translocation of two genes on chromosome 9 and 22. The new chromosome that this forms is called the _______ chromosome

Select one of the following:

  • Philadelphia

  • Cathedral City

  • Dairylee

Explanation

Question 4 of 12

1

Select some of the functions of a tumour-suppressor gene's encoded protein.

Select one or more of the following:

  • slow down cell division

  • repair DNA mistakes

  • trigger apoptosis

  • activate immune surveillance

Explanation

Question 5 of 12

1

Caretaker genes are a class of tumour suppressor genes however, they do not regulate cell division. Instead they...

Select one of the following:

  • Recognise and repair DNA damage, therefore being directly responsible for cancer development

  • Recognise and repair DNA damage, however, not being directly responsible for cancer development

Explanation

Question 6 of 12

1

Bystander or passenger mutations are mutated genes that are not related to the growth or development of a cancer.

Select one of the following:

  • True

  • False

Explanation

Question 7 of 12

1

Differentiation, increasingly autonomous growth and aggressive behaviour are trates associated with a cancer in ______ stage of carcinogenesis

Select one of the following:

  • inititation

  • promotion

  • progression

Explanation

Question 8 of 12

1

Some pathogens are capable of establishing chronic infections at certain sites in the body. This creates a local environment where even uninfected cells are at a greater risk of becoming cancerous.

Select one of the following:

  • True

  • False

Explanation

Question 9 of 12

1

There are four types of genetic disorder. Which of the following best describes each of these four types

Select one or more of the following:

  • autoimmune

  • single gene

  • multifactorial

  • chromosomal

  • mitochondrial

Explanation

Question 10 of 12

1

Down's syndrome frequency increases with paternal age.

Select one of the following:

  • True

  • False

Explanation

Question 11 of 12

1

Tumour antigens may be specific to a tumour (TSA), or just occur more frequently in a tumour (TAA). Both must be capable of inducing an antibody or cell-medicated response.

Select one of the following:

  • True

  • False

Explanation

Question 12 of 12

1

An immune response against self antigen(s) that results in a disease causing tissue damage or disturbed physiological function best describes...

Select one of the following:

  • Immune Response

  • Autoimmunity

  • Self-tolerance

Explanation