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BSc (Hons) Biology Quiz on Cancer & Autoimmune Disease: Quiz the Fifth, created by Sami-Jaine on 09/05/2013.

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Cancer & Autoimmune Disease: Quiz the Fifth

Question 1 of 10

1

Which of the following are considered the "rules of direct causal association"

Select one or more of the following:

  • not all patients with the type of cancer in question have to have previously been infected with the virus

  • every cancer of this type carries the virus' genetic information in every malignant cell

  • The virus itself, or individual virus genes can often "transform" the growth of normal cells in cell culture

  • all patients with the type of cancer in question have previously infected with the virus

Explanation

Question 2 of 10

1

Which of the following contribute to the breakdown of tolerance?

Select one of the following:

  • Failure to delete auto-reactive lymphocytes (peripheral and central tolerance failure)

  • Molecular mimicry

  • Abnormal presentation of self antigens

  • Epitope spreading

  • Polyclonal lymphocyte activation

  • All of the above

  • None of the above. This is a trick question.

Explanation

Question 3 of 10

1

Cigarette smoke is an irritant to the respiratory epithelium. It paralyses the sensitive cilia on the columnar cells and so the cells are (reversibly) replaced by the more robust squamous cells. This is an example of...

Select one of the following:

  • metaplasia

  • atrophy

  • dysplasia

Explanation

Question 4 of 10

1

Dysplasia is the (reversible) state where a cell can change in which of the following ways...

Select one or more of the following:

  • cell type

  • size

  • shape

  • organisation

  • colour

Explanation

Question 5 of 10

1

Dysplasia is considered...

Select one of the following:

  • cancerous

  • benign

  • precancerous

Explanation

Question 6 of 10

1

Which of the following are true?

Select one or more of the following:

  • Carcinomas are tumours of the epithelium

  • Lymphomas, leukaemias and myelomas are haematological tumours

  • Benign tumours can be fatal

  • Sarcomas are tumours of muscle, cartilage, bone etc

  • Benign tumours are still functional tissues

Explanation

Question 7 of 10

1

cancers arise in single cells. this makes them clonal in origin.
because all the cells in the cancer arose from the proliferation of this one cell, cancers are said to be

Select one of the following:

  • monoclonal

  • polyclonal

Explanation

Question 8 of 10

1

Is a malignant cell able to perform specialist tasks?

Select one of the following:

  • Yes

  • No

Explanation

Question 9 of 10

1

Distant growths originating from one tumour are called metastases?

Select one of the following:

  • Yes

  • No

Explanation

Question 10 of 10

1

Which of the following have an influence upon cancer development

Select one or more of the following:

  • Geographical location

  • Dietary fats, vitamins an fibres

  • Smoking, sex hormones, age, family history

Explanation

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