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Chiral synthesis in the laboratory is often very ( difficult, straightforward, fast ). It is even harder to scale up to industrial scale. Two approaches to obtaining pure chiral molecules are ( Chiral separation, chiral synthesis, HPLC/MS ) (use a physical method e.g chromatography to separate the desired stereoisomer from a mixture) and ( The Chiral Pool, The chemical pool, chiral separation, chiral splitting ) (use a starting material that already contains a chriral centre.)